71-775
Tocris™ NR 7h
Manufacturer: Tocris™
CAS Number: 2550399-06-7
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 71-775-Each-of-1 | In Stock | ₹ 45,004.56 |
71-775 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,004.56
GST (18%): ₹ 8,100.821
Total Price: ₹ 53,105.381
Chemical Name or Material
3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2 H)-yl)-N-(4-(1-(4-((4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)amino)-4-oxobutyl)-1 H-1,2,3-triazol-4-yl)butyl)-4-methylbenzamide
Quantity
5 mg
Molecular Formula
C48H50BrF2N9O8
Purity
97%
CAS
2550399-06-7
Target
Active Degraders
Formula Weight
3636
Related Products
Description
- NR 7h is a potent and selective p38α and p38β Degrader (PROTAC™) (DC50 < 50 nM)
- Displays no significant degradation of p38γ, p38δ, JNK1/2 or ERK1/2
- Inhibits phosphorylation of MK2 in UV-treated cancer cells and LPS-stimulated bone marrow-derived macrophages (BMDM)
- Exhibits similar effect to p38α gene knockout in BBL358 cells
- NR 7h impairs replication of Mayaro virus in human dermal fibroblasts and HeLa cells
- Active in vivo
- PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2 H)-yl)-N-(4-(1-(4-((4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)amino)-4-oxobutyl)-1 H-1,2,3-triazol-4-yl)butyl)-4-methylbenzamide
Quantity: 5 mg
Molecular Formula: C48H50BrF2N9O8
Purity: 97%
CAS: 2550399-06-7
Target: Active Degraders
Formula Weight: 3636
Chemical Name or Material:
3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2 H)-yl)-N-(4-(1-(4-((4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)amino)-4-oxobutyl)-1 H-1,2,3-triazol-4-yl)butyl)-4-methylbenzamide
Quantity:
5 mg
Molecular Formula:
C48H50BrF2N9O8
Purity:
97%
CAS:
2550399-06-7
Target:
Active Degraders
Formula Weight:
3636
Chemical Name or Material: __
Quantity: 100 μg
Molecular Formula: __
Purity: __
CAS: __
Target: __
Formula Weight: __
Chemical Name or Material:
__
Quantity:
100 μg
Molecular Formula:
__
Purity:
__
CAS:
__
Target:
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Formula Weight:
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Chemical Name or Material: tert-Butyl ((S)-1-(((S)-1-cyclohexyl-2-((S)-2-(4-(3-hydroxybenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate
Quantity: 50 mg
Molecular Formula: C31H42N4O6S
Purity: 0.95
CAS: 2095244-42-9
Target: Degrader Building Blocks
Formula Weight: __
Chemical Name or Material:
tert-Butyl ((S)-1-(((S)-1-cyclohexyl-2-((S)-2-(4-(3-hydroxybenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate
Quantity:
50 mg
Molecular Formula:
C31H42N4O6S
Purity:
0.95
CAS:
2095244-42-9
Target:
Degrader Building Blocks
Formula Weight:
__
Chemical Name or Material: __
Quantity: 1 L Kit
Molecular Formula: __
Purity: __
CAS: __
Target: __
Formula Weight: __
Chemical Name or Material:
__
Quantity:
1 L Kit
Molecular Formula:
__
Purity:
__
CAS:
__
Target:
__
Formula Weight:
__