64-601-0

Tocris Bioscience™ ABX 464

Manufacturer: Fischer Scientific

CAS Number: 1258453-75-6

Select a Size

Pack Size SKU Availability Price
Each of 1 64-601-0-Each-of-1 In Stock ₹ 20,743.17

64-601-0 - Each of 1

₹ 20,743.17

In Stock

Quantity

1

Base Price: ₹ 20,743.17

GST (18%): ₹ 3,733.771

Total Price: ₹ 24,476.941

Chemical Name or Material

8-Chloro-N-[4-(trifluoromethoxy)phenyl]-2-quinolinamine

Quantity

10 mg

Molecular Formula

C16H10ClF3N2O

CAS

1258453-75-6

Target

DNA, RNA and Protein Synthesis Compounds

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
7250156
Tocris Bioscience™ ABX 464
Fischer Scientific --
64-605-0
Tocris Bioscience™ ABX 464
Fischer Scientific ₹ 87,041.90
50-193-1977
Medchemexpress LLC HY-100870 5mg Medchemexpress, ABX464 CAS:1258453-75-6 Purity:>98%
Medchemexpress LLC ₹ 10,331.37
AE43523
1258453-75-6 | ABX-464
A2B Chem ₹ 7,529.28 - ₹ 25,924.68

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Description

  • ABX 464 is an HIV RNA splicing modulator; it selectively enhances the splicing of HIV RNA in infected human PBMCs and inhibits viral replication, with no global effect on cellular splicing
  • ABX 464 inhibits replication of HIV strains harboring mutations associated with drug-resistance
  • ABX 464 binds the cap binding complex (CBC) and upregulates miR-124 expression in vitro and decreases expression of miR-124 target genes, MCP-1, CXCL-1, SERPIN-E1 in macrophages
  • It also decreases the number of Th17 cells, as well as IL-6 soluble receptor in CD4+ T cells
  • In HIV infected humanized mice, treatment with ABX 464 reduces viral load
  • Anti-inflammatory.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

Img

Fischer Scientific

64-601-0

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Chemical Name or Material:
8-Chloro-N-[4-(trifluoromethoxy)phenyl]-2-quinolinamine

Quantity:
10 mg

Molecular Formula:
C16H10ClF3N2O

CAS:
1258453-75-6

Target:
DNA, RNA and Protein Synthesis Compounds

Purity:
0.98

Img

Fischer Scientific

64-605-0

--


Chemical Name or Material:
8-Chloro-N-[4-(trifluoromethoxy)phenyl]-2-quinolinamine

Quantity:
50 mg

Molecular Formula:
C16H10ClF3N2O

CAS:
1258453-75-6

Target:
DNA, RNA and Protein Synthesis Compounds

Purity:
0.98

Img

Tocris Bioscience™

64-611

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Chemical Name or Material:
(T-4)-[4-[[3-[[4-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN-1-oxopropyl]-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinonato]difluoroboron

Quantity:
1 mg

Molecular Formula:
C34H32BF3N6O3

CAS:
1380359-84-1

Target:
__

Purity:
90%

Img

R&D Systems

64-632-5

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Chemical Name or Material:
PROTAC Toolbox

Quantity:
25 mg

Molecular Formula:
C30H45N5O7S.2HCl

CAS:
2097971-11-2

Target:
__

Purity:
95%