64-802-5

Tocris Bioscience™ GSK 583

Manufacturer: Fischer Scientific

CAS Number: 1346547-00-9

Select a Size

Pack Size SKU Availability Price
Each of 1 64-802-5-Each-of-1 In Stock ₹ 37,063.16

64-802-5 - Each of 1

₹ 37,063.16

In Stock

Quantity

1

Base Price: ₹ 37,063.16

GST (18%): ₹ 6,671.369

Total Price: ₹ 43,734.529

Chemical Name or Material

6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine

Quantity

25 mg

Purity

98%

CAS

1346547-00-9

Molecular Formula

C20H19FN4O2S

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ GSK 583
-- --
Tocris Bioscience™ GSK 583
-- ₹ 9,704.56
Medchemexpress LLC HY-100339 2mg , GSK583 CAS:1346547-00-9 Purity:>98%
-- ₹ 7,569.45
Thermo Scientific™ GSK583, 95%
-- ₹ 38,359.00
Sigma Aldrich Fine Chemicals Biosciences GSK583 >=98% (HPLC) | 1346547-00-9 | 5MG
-- ₹ 11,774.70
Sigma Aldrich Fine Chemicals Biosciences GSK583 >=98% (HPLC) | 1346547-00-9 | 25MG
-- ₹ 46,564.80
1346547-00-9 | Gsk583
-- ₹ 3,560.00 - ₹ 1,90,994.00

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Description

  • Potent RIP2 kinase inhibitor (IC50 values are 2 and 5 nM at rat and human kinases, respectively)
  • Displays selectivity for RIP2K over p38α, VEGFR2 and a panel of 300 kinases
  • Exhibits some inhibition at BRK and Aurora A
  • Also displays similar binding affinity, but no detectable functional activity at RIP3
  • Active in vivo
  • Moderately orally bioavailable and cell permeable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C