7146002
Tocris Bioscience™ GSK 583
Potent RIP2 kinase inhibitor; orally bioavailable and cell permeable
Manufacturer: Fischer Scientific
CAS Number: 1346547-00-9
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Chemical Name or Material
6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine
CAS
1346547-00-9
Molecular Formula
C20H19FN4O2S
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ GSK 583 | Fischer Scientific | ₹ 9,704.56 | |
| | Tocris Bioscience™ GSK 583 | Fischer Scientific | ₹ 37,063.16 | |
 | Medchemexpress LLC HY-100339 2mg , GSK583 CAS:1346547-00-9 Purity:>98% | Medchemexpress LLC | ₹ 7,569.45 | |
| | Thermo Scientific™ GSK583, 95% | Thermo Scientific™ | ₹ 38,359.00 | |
 | Sigma Aldrich Fine Chemicals Biosciences GSK583 >=98% (HPLC) | 1346547-00-9 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 11,774.70 | |
 | Sigma Aldrich Fine Chemicals Biosciences GSK583 >=98% (HPLC) | 1346547-00-9 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 46,564.80 | |
 | 1346547-00-9 | Gsk583 | A2B Chem | ₹ 3,560.00 - ₹ 1,90,994.00 |
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Description
- Potent RIP2 kinase inhibitor (IC50 values are 2 and 5 nM at rat and human kinases, respectively)
- Displays selectivity for RIP2K over p38α, VEGFR2 and a panel of 300 kinases
- Exhibits some inhibition at BRK and Aurora A
- Also displays similar binding affinity, but no detectable functional activity at RIP3
- Active in vivo
- Moderately orally bioavailable and cell permeable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine
CAS: 1346547-00-9
Molecular Formula: C20H19FN4O2S
Purity: 98%
Chemical Name or Material:
6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine
CAS:
1346547-00-9
Molecular Formula:
C20H19FN4O2S
Purity:
98%
Chemical Name or Material: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one hydrochloride
CAS: 148849-67-6
Molecular Formula: C27H36N2O5.HCl
Purity: 98%
Chemical Name or Material:
3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one hydrochloride
CAS:
148849-67-6
Molecular Formula:
C27H36N2O5.HCl
Purity:
98%
Chemical Name or Material: __
CAS: __
Molecular Formula: __
Purity: __
Chemical Name or Material:
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CAS:
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Molecular Formula:
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Purity:
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Chemical Name or Material: N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamide
CAS: 1913252-04-6
Molecular Formula: C30H38N8O2
Purity: 98%
Chemical Name or Material:
N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamide
CAS:
1913252-04-6
Molecular Formula:
C30H38N8O2
Purity:
98%