7161631
Tocris Bioscience™ GSK'872
Potent and selective RIP3 kinase inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1346546-69-7
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Chemical Name or Material
N-5-Benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine
Molecular Formula
C19H17N3O2S2
Purity
98%
CAS
1346546-69-7
Formula Weight
383.49
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ GSK'872 | Fischer Scientific | ₹ 22,739.50 | |
| | Tocris Bioscience™ GSK'872 | Fischer Scientific | ₹ 94,518.00 | |
 | Selleck Chemical LLC GSK'872 (GSK2399872A) 5mg 1346546-69-7 | Selleck Chemical LLC | ₹ 15,699.60 | |
 | Medchemexpress LLC HY-101872 50mg , GSK-872 CAS:1346546-69-7 Purity:>98% | Medchemexpress LLC | ₹ 36,445.50 | |
 | Medchemexpress LLC HY-101872 10mg Medchemexpress, GSK-872 CAS:1346546-69-7 Purity:>98% | Medchemexpress LLC | ₹ 14,017.50 | |
 | Medchemexpress LLC GSK-872 | 1346546-69-7 | MFCD30481302 | 5mg | Medchemexpress LLC | ₹ 8,410.50 | |
 | N-(1,3-benzothiazol-5-yl)-6-(propane-2-sulfonyl)-1,4-dihydroquinolin-4-imine | Aaron Chemicals LLC | ₹ 1,602.00 - ₹ 53,845.00 | |
 | 1346546-69-7 | N-(1,3-benzothiazol-5-yl)-6-(propane-2-sulfonyl)-1,4-dihydroquinolin-4-imine | A2B Chem | ₹ 2,136.00 - ₹ 22,072.00 |
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Description
- Potent and selective receptor activating protein kinase 3 (RIP3) inhibitor (IC50 = 1.3 nM) Exhibits >1000-fold selectivity for RIP3 over a panel of 300 other kinases including RIP1 Inhibits TNF-induced cell death in 3T3-SA cells and TLR3-induced necrosis in fibroblasts in vitro Blocks necroptosis of primary human neutrophils from whole blood Also induces apoptosis at higher concentrations (3 to 10 μM)
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N-5-Benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine
Molecular Formula: C19H17N3O2S2
Purity: 98%
CAS: 1346546-69-7
Formula Weight: 383.49
Chemical Name or Material:
N-5-Benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine
Molecular Formula:
C19H17N3O2S2
Purity:
98%
CAS:
1346546-69-7
Formula Weight:
383.49
Chemical Name or Material: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one
Molecular Formula: C25H24N6O2
Purity: 98%
CAS: 936563-96-1
Formula Weight: 440.5
Chemical Name or Material:
1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one
Molecular Formula:
C25H24N6O2
Purity:
98%
CAS:
936563-96-1
Formula Weight:
440.5
Chemical Name or Material: 1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one
Molecular Formula: C18H17NO4
Purity: 98%
CAS: 186611-52-9
Formula Weight: 311.33
Chemical Name or Material:
1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one
Molecular Formula:
C18H17NO4
Purity:
98%
CAS:
186611-52-9
Formula Weight:
311.33
Chemical Name or Material: 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
Molecular Formula: C10H8O3S
Purity: 98%
CAS: 651005-90-2
Formula Weight: 208.23
Chemical Name or Material:
2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
Molecular Formula:
C10H8O3S
Purity:
98%
CAS:
651005-90-2
Formula Weight:
208.23