65-775-0
Tocris™ Pyridone 6
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 65-775-0-Each-of-1 | In Stock | ₹ 1,00,533.00 |
65-775-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,00,533.00
GST (18%): ₹ 18,095.94
Total Price: ₹ 1,18,628.94
Synonym
JAK inhibitor I
Molecular Formula
C18H16FN3O
Product Type
Inhibitor
Quantity
50 mg
Formula Weight
309.34
Purity
98%
Related Products
Description
- Pyridone 6 is a potent pan-JAK inhibitor; ATP-competitive inhibitor of JAK 1/2/3 and Tyk2 (IC50 values are 1, 5, 15 and 1 nM, respectively)
- Inhibits other kinases tested at 130 nM to >10 μM
- Inhibits IL-2- and IL-4-dependent proliferation of CTLL cells and blocks STAT5 phosphorylation
- Also inhibits Th1 and Th2 development, and promotes Th17 differentiation from naive T cells
- When used in combination with Retinoic acid, LY 294002 and CCG 1423, it induces intermediate mesoderm differentiation from ESCs
- Inhibits growth of primary myeloma cells grown in the presence of bone marrow stromal cells
- Cell-permeable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Synonym: JAK inhibitor I
Molecular Formula: C18H16FN3O
Product Type: Inhibitor
Quantity: 50 mg
Formula Weight: 309.34
Purity: 98%
Synonym:
JAK inhibitor I
Molecular Formula:
C18H16FN3O
Product Type:
Inhibitor
Quantity:
50 mg
Formula Weight:
309.34
Purity:
98%
Synonym: __
Molecular Formula: C26H19F5N6OS
Product Type: __
Quantity: 25 mg
Formula Weight: 558.53
Purity: 98%
Synonym:
__
Molecular Formula:
C26H19F5N6OS
Product Type:
__
Quantity:
25 mg
Formula Weight:
558.53
Purity:
98%
Synonym: __
Molecular Formula: C26H19F5N6OS
Product Type: __
Quantity: 5 mg
Formula Weight: 558.53
Purity: 98%
Synonym:
__
Molecular Formula:
C26H19F5N6OS
Product Type:
__
Quantity:
5 mg
Formula Weight:
558.53
Purity:
98%
Synonym: __
Molecular Formula: C14H11N3O6
Product Type: __
Quantity: 25 mg
Formula Weight: 317.25
Purity: 98%
Synonym:
__
Molecular Formula:
C14H11N3O6
Product Type:
__
Quantity:
25 mg
Formula Weight:
317.25
Purity:
98%