68-925-0
Tocris™ RIPGBM
Manufacturer: Fischer Scientific
CAS Number: 355406-76-7
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 68-925-0-Each-of-1 | In Stock | ₹ 92,798.38 |
68-925-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 92,798.38
GST (18%): ₹ 16,703.708
Total Price: ₹ 1,09,502.088
Chemical Name or Material
N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide
Quantity
50 mg
Molecular Formula
C26H21FN2O3
Purity
98%
CAS
355406-76-7
Target
RIP Kinase Inhibitors
Formula Weight
7272
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris™ RIPGBM | Fischer Scientific | -- | |
| | Tocris™ RIPGBM | Fischer Scientific | ₹ 22,033.41 | |
 | eMolecules Medchem Express / RIPGBM / 5mg / 536983973 / HY-122910 / / 355406-76-7 / MFCD05670032 / 428.463 / C26H21FN2O3 | eMolecules | ₹ 8,312.15 |
Related Products
Description
- RIPK2 modulator, pro-drug of cRIPGM
- cRIPGM binds RIPK2 (apparent Kd = 2.3 μM)
- Selectively induces apoptosis in glioblastoma multiforme cancer stem cell lines (EC50 is <500 nM)
- Five-fold selective for CSCs compared with control cell types
- Reduces the formation of a prosurvival RIPK2/ TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex
- Inhibits tumor formation and growth in vivo
- Orally bioavailable and brain penetrant.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide
Quantity: 50 mg
Molecular Formula: C26H21FN2O3
Purity: 98%
CAS: 355406-76-7
Target: RIP Kinase Inhibitors
Formula Weight: 7272
Chemical Name or Material:
N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide
Quantity:
50 mg
Molecular Formula:
C26H21FN2O3
Purity:
98%
CAS:
355406-76-7
Target:
RIP Kinase Inhibitors
Formula Weight:
7272
Chemical Name or Material: 3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Quantity: 10 mg
Molecular Formula: C16H12F5N3O
Purity: 98%
CAS: 2137047-43-7
Target: __
Formula Weight: __
Chemical Name or Material:
3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Quantity:
10 mg
Molecular Formula:
C16H12F5N3O
Purity:
98%
CAS:
2137047-43-7
Target:
__
Formula Weight:
__
Chemical Name or Material: 3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Quantity: 50 mg
Molecular Formula: C16H12F5N3O
Purity: 98%
CAS: 2137047-43-7
Target: __
Formula Weight: __
Chemical Name or Material:
3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Quantity:
50 mg
Molecular Formula:
C16H12F5N3O
Purity:
98%
CAS:
2137047-43-7
Target:
__
Formula Weight:
__
Chemical Name or Material: 5-[2-(2-(3-Fluorophenyl)ethynyl]-N-[(1R)-2-hydroxy-1,2-dimethylpropyl]-2-pyridinecarboxamide
Quantity: 10 mg
Molecular Formula: C19H19FN2O2
Purity: 98%
CAS: 1428630-85-6
Target: __
Formula Weight: __
Chemical Name or Material:
5-[2-(2-(3-Fluorophenyl)ethynyl]-N-[(1R)-2-hydroxy-1,2-dimethylpropyl]-2-pyridinecarboxamide
Quantity:
10 mg
Molecular Formula:
C19H19FN2O2
Purity:
98%
CAS:
1428630-85-6
Target:
__
Formula Weight:
__