70-512-5

Tocris NFκB p50 Transcription Factor Assay

Manufacturer: Tocris

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Pack Size SKU Availability Price
Each of 1 70-512-5-Each-of-1 In Stock ₹ 37,090.26

70-512-5 - Each of 1

₹ 37,090.26

In Stock

Quantity

1

Base Price: ₹ 37,090.26

GST (18%): ₹ 6,676.247

Total Price: ₹ 43,766.507

Quantity

25 mg

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Description

  • Tasquinimod is a high affinity negative allosteric modulator of HDAC4 (Kd = 10 - 30 nM)
  • Binds the regulatory Zn2+ binding domain of HDAC4
  • Suppresses hypoxia-induced decrease in histone acetylation in human prostate cancer cells in vitro
  • Also binds S100A9
  • Antiangiogenic
  • Inhibits endothelial sprouting in vitro and growth of prostate tumor xenografts in nude mice
  • Orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store kit components at the temperatures indicated on the labels and insert until their expiration dateStore HeLa Whole Cell Extract at -80°C. Avoid repeated freeze-thaw cycles. Stable (at -80°C for 6 months)

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