70-645-0
Tocris™ Ruxolitinib
Manufacturer: Tocris™
CAS Number: 941678-49-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-645-0-Each-of-1 | In Stock | ₹ 30,373.80 |
70-645-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,373.80
GST (18%): ₹ 5,467.284
Total Price: ₹ 35,841.084
Chemical Name or Material
(3 R)-3-Cyclopentyl-3-[4-(7 H-pyrrolo[2,3-d]pyrimidin-4-yl)-1 H-pyrazol-1-yl]propanenitrile
Quantity
50 mg
Molecular Formula
C17H18N6
Purity
98%
CAS
941678-49-5
Target
JAK Kinase Inhibitors
Formula Weight
2323
Other Options
Related Products
Description
- Ruxolitinib is a potent and selective JAK1/2 inhibitor (IC50 values are 3.3 and 2.8 nM, respectively)
- Exhibits selectivity for JAK1/2 over Tyk2 and JAK3 (∼6-fold and >130-fold, respectively)
- Exhibits no significant inhibition against a commercial panel of 26 additional kinases
- Inhibits JAK2V617F-mediated signaling and proliferation in Ba/F3 cells and HEL cells
- Increases survival rates in a JAK2V617F-driven mouse model
- Identified as targeting human host proteins that interact with SARS-CoV-2
- Orally bioavailable
- Phosphate salt (Cat
- No
- 7048) also available.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: (3 R)-3-Cyclopentyl-3-[4-(7 H-pyrrolo[2,3-d]pyrimidin-4-yl)-1 H-pyrazol-1-yl]propanenitrile
Quantity: 50 mg
Molecular Formula: C17H18N6
Purity: 98%
CAS: 941678-49-5
Target: JAK Kinase Inhibitors
Formula Weight: 2323
Chemical Name or Material:
(3 R)-3-Cyclopentyl-3-[4-(7 H-pyrrolo[2,3-d]pyrimidin-4-yl)-1 H-pyrazol-1-yl]propanenitrile
Quantity:
50 mg
Molecular Formula:
C17H18N6
Purity:
98%
CAS:
941678-49-5
Target:
JAK Kinase Inhibitors
Formula Weight:
2323
Chemical Name or Material: __
Quantity: 10 kU
Molecular Formula: __
Purity: __
CAS: __
Target: __
Formula Weight: __
Chemical Name or Material:
__
Quantity:
10 kU
Molecular Formula:
__
Purity:
__
CAS:
__
Target:
__
Formula Weight:
__
Chemical Name or Material: N-(4-Bromophenyl)-4-phenyl-2-thiazolamine
Quantity: 50 mg
Molecular Formula: C15H11BrN2S
Purity: 98%
CAS: 108237-91-8
Target: __
Formula Weight: __
Chemical Name or Material:
N-(4-Bromophenyl)-4-phenyl-2-thiazolamine
Quantity:
50 mg
Molecular Formula:
C15H11BrN2S
Purity:
98%
CAS:
108237-91-8
Target:
__
Formula Weight:
__
Chemical Name or Material: __
Quantity: 10 mL
Molecular Formula: __
Purity: __
CAS: __
Target: __
Formula Weight: __
Chemical Name or Material:
__
Quantity:
10 mL
Molecular Formula:
__
Purity:
__
CAS:
__
Target:
__
Formula Weight:
__