63-485

PF 06424439

Manufacturer: R&D Systems

CAS Number: 1469284-79-4

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Pack Size SKU Availability Price
Each of 1 63-485-Each-of-1 In Stock ₹ 9,625.50

63-485 - Each of 1

₹ 9,625.50

In Stock

Quantity

1

Base Price: ₹ 9,625.50

GST (18%): ₹ 1,732.59

Total Price: ₹ 11,358.09

Chemical Name or Material

[(3R)-1-[2-[1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl]-3H-imidazo[4,5-b]pyridin-5-yl]-3-piperidinyl]-1-pyrrolidinylmethanone methanesulfonate

Assay Percent Range

>98%

Molecular Formula

C22H26ClN7O.CH4O3S

CAS

1469284-79-4

Quantity

5 mg

Formula Weight

Observed MW: 536.05

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Description

  • PF 06424439 is a potent and selective DGAT2 inhibitor (IC50 = 14 nM)
  • Exhibits no significant activity at MGAT1-3 or DGAT1
  • Reduces triglyderide synthesis in human hepatocytes in vitro
  • Reduces plasma triglyceride and cholesterol levels in a rat dyslipidemia model
  • Orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Desiccate at Room Temperature

Compare Similar Items

Show Difference

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R&D Systems

63-485

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Chemical Name or Material:
[(3R)-1-[2-[1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl]-3H-imidazo[4,5-b]pyridin-5-yl]-3-piperidinyl]-1-pyrrolidinylmethanone methanesulfonate

Assay Percent Range:
>98%

Molecular Formula:
C22H26ClN7O.CH4O3S

CAS:
1469284-79-4

Quantity:
5 mg

Formula Weight:
Observed MW: 536.05

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Fischer Scientific

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Chemical Name or Material:
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide

Assay Percent Range:
__

Molecular Formula:
C24H23ClFN5O2

CAS:
257933-82-7

Quantity:
25 mg

Formula Weight:
467.92

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Fischer Scientific

63-495

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Chemical Name or Material:
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide

Assay Percent Range:
__

Molecular Formula:
C24H23ClFN5O2

CAS:
257933-82-7

Quantity:
5 mg

Formula Weight:
467.92

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eBioscience

63-504-042

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Chemical Name or Material:
__

Assay Percent Range:
__

Molecular Formula:
__

CAS:
__

Quantity:
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Formula Weight:
__