48-205-RD
PF 04691502, Tocris Bioscience™
Manufacturer: R&D Systems
CAS Number: 1013101-36-4
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Chemical Name or Material
2-Amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxy-3-pyridinyl)-4-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one
Assay Percent Range
>98%
Molecular Formula
C22H27N5O4
CAS
1013101-36-4
Quantity
5 mg
Formula Weight
Observed MW: 425.48
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules PF-04691502 | 1013101-36-4 | MFCD18782794 | 0.1g | eMolecules | ₹ 60,860.87 | |
 | Sigma Aldrich Fine Chemicals Biosciences PF-04691502 >=98% (HPLC) | 1013101-36-4 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 50,730.00 | |
 | Medchemexpress LLC HY-15177 100mg , PF-04691502 CAS:1013101-36-4 Purity:>98% | Medchemexpress LLC | ₹ 46,257.75 |
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Description
- PF 04691502 is a potent and selective dual ATP-competitive PI 3-K/mTOR inhibitor (Ki values are 1.6, 1.8, 1.9, 2.1 and 16 nM for human PI 3-K δ, α, γ, β, and mTOR, respectively)
- Displays no significant inhibitory activity at more than 80 protein kinases (concentration ≥ 10 μM) including hVps34, PI 3-K downstream kinases, and MAPK family members
- Orally bioavailable
- Induces robust cell cycle arrest at the G1 phase in U87MG cancer cells and antitumor activity in SKOV3 ovarian cancer xenograft models.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 2-Amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxy-3-pyridinyl)-4-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one
Assay Percent Range: >98%
Molecular Formula: C22H27N5O4
CAS: 1013101-36-4
Quantity: 5 mg
Formula Weight: Observed MW: 425.48
Chemical Name or Material:
2-Amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxy-3-pyridinyl)-4-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one
Assay Percent Range:
>98%
Molecular Formula:
C22H27N5O4
CAS:
1013101-36-4
Quantity:
5 mg
Formula Weight:
Observed MW: 425.48
Chemical Name or Material: __
Assay Percent Range: __
Molecular Formula: C21H26N2O7
CAS: 66085-59-4
Quantity: 25 mg
Formula Weight: 418.4g/mol
Chemical Name or Material:
__
Assay Percent Range:
__
Molecular Formula:
C21H26N2O7
CAS:
66085-59-4
Quantity:
25 mg
Formula Weight:
418.4g/mol
Chemical Name or Material: __
Assay Percent Range: __
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Quantity: 10 mL
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Quantity:
10 mL
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Quantity: 100 μg
Formula Weight: __
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Quantity:
100 μg
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