48-205-RD

PF 04691502, Tocris Bioscience™

Manufacturer: R&D Systems

CAS Number: 1013101-36-4

The price for this product is unavailable. Please request a quote

Chemical Name or Material

2-Amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxy-3-pyridinyl)-4-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one

Assay Percent Range

>98%

Molecular Formula

C22H27N5O4

CAS

1013101-36-4

Quantity

5 mg

Formula Weight

Observed MW: 425.48

Other Options

Image Product Name Manufacturer Price Range
50-217-8874
eMolecules​ PF-04691502 | 1013101-36-4 | MFCD18782794 | 0.1g
eMolecules​ ₹ 58,508.49
50-186-1679
Sigma Aldrich Fine Chemicals Biosciences PF-04691502 >=98% (HPLC) | 1013101-36-4 | 25MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 48,769.20
50-225-9740
Medchemexpress LLC HY-15177 100mg , PF-04691502 CAS:1013101-36-4 Purity:>98%
Medchemexpress LLC ₹ 44,469.81

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Description

  • PF 04691502 is a potent and selective dual ATP-competitive PI 3-K/mTOR inhibitor (Ki values are 1.6, 1.8, 1.9, 2.1 and 16 nM for human PI 3-K δ, α, γ, β, and mTOR, respectively)
  • Displays no significant inhibitory activity at more than 80 protein kinases (concentration ≥ 10 μM) including hVps34, PI 3-K downstream kinases, and MAPK family members
  • Orally bioavailable
  • Induces robust cell cycle arrest at the G1 phase in U87MG cancer cells and antitumor activity in SKOV3 ovarian cancer xenograft models.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

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R&D Systems

48-205-RD

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Chemical Name or Material:
2-Amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxy-3-pyridinyl)-4-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one

Assay Percent Range:
>98%

Molecular Formula:
C22H27N5O4

CAS:
1013101-36-4

Quantity:
5 mg

Formula Weight:
Observed MW: 425.48

Img

MilliporeSigma™

48-220-025MG

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Chemical Name or Material:
__

Assay Percent Range:
__

Molecular Formula:
C21H26N2O7

CAS:
66085-59-4

Quantity:
25 mg

Formula Weight:
418.4g/mol

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R&D Systems™

48-229-608

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Chemical Name or Material:
__

Assay Percent Range:
__

Molecular Formula:
__

CAS:
__

Quantity:
10 mL

Formula Weight:
__

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Invitrogen

48-230-0

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Chemical Name or Material:
__

Assay Percent Range:
__

Molecular Formula:
__

CAS:
__

Quantity:
100 μg

Formula Weight:
__