7082165
Tocris Bioscience™ NS 8593 Hydrochloride
Selective negative modulator of KCa2 (SK) channels; inhibits SK currents
Manufacturer: Fischer Scientific
CAS Number: 875755-24-1
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Chemical Name or Material
NS 8593 hydrochloride
Synonym
N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride
Molecular Formula
C17H17N3·HCl
Physical Form
Solid
Purity
>98%
CAS
875755-24-1
Solubility
Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight
299.8
Product Type
Bioactive Small Molecule
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ NS 8593 Hydrochloride | Fischer Scientific | ₹ 27,857.00 | |
| | Tocris Bioscience™ NS 8593 Hydrochloride | Fischer Scientific | ₹ 1,12,318.00 | |
 | Medchemexpress LLC HY-110105 5mg Medchemexpress, NS8593 (hydrochloride) CAS:875755-24-1 Purity:>98% | Medchemexpress LLC | ₹ 10,279.50 | |
 | NS8593 (hydrochloride) | ChemScene | ₹ 10,680.00 - ₹ 42,720.00 | |
 | 875755-24-1 | NS8593 hydrochloride | A2B Chem | ₹ 2,403.00 - ₹ 33,375.00 |
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Description
- Selective KCa2 (SK) channel negative modulator; inhibits SK channel currents (Kd values are 0.42, 0.6 and 0.73 μM for SK1, SK2 and SK3 respectively at 0.5 μM Ca2+)
- Exhibits selectivity for SK channels over KCa1.1 (BK), KCa3.1 (IK), Kv, Nav and Cav channels
- Inhibits afterhyperpolarization in hippocampal slices.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
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Chemical Name or Material: NS 8593 hydrochloride
Synonym: N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride
Molecular Formula: C17H17N3·HCl
Physical Form: Solid
Purity: >98%
CAS: 875755-24-1
Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight: 299.8
Product Type: Bioactive Small Molecule
Chemical Name or Material:
NS 8593 hydrochloride
Synonym:
N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride
Molecular Formula:
C17H17N3·HCl
Physical Form:
Solid
Purity:
>98%
CAS:
875755-24-1
Solubility:
Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight:
299.8
Product Type:
Bioactive Small Molecule
Chemical Name or Material: Edaglitazone
Synonym: 5-[[4-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethoxy]benzo[b]thien-7-yl]methyl]-2,4-thiazolidinedione
Molecular Formula: C24H20N2O4S2
Physical Form: Solid
Purity: >98%
CAS: 213411-83-7
Solubility: Soluble to 100mM in DMSO
Formula Weight: 464.56
Product Type: Bioactive Small Molecule
Chemical Name or Material:
Edaglitazone
Synonym:
5-[[4-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethoxy]benzo[b]thien-7-yl]methyl]-2,4-thiazolidinedione
Molecular Formula:
C24H20N2O4S2
Physical Form:
Solid
Purity:
>98%
CAS:
213411-83-7
Solubility:
Soluble to 100mM in DMSO
Formula Weight:
464.56
Product Type:
Bioactive Small Molecule
Chemical Name or Material: ML 179
Synonym: 3-Cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione
Molecular Formula: C21H25F3N4O2
Physical Form: Crystalline Solid
Purity: >99%
CAS: 1883548-87-5
Solubility: Soluble to 50mM in DMSO
Formula Weight: 422.44
Product Type: Bioactive Small Molecule
Chemical Name or Material:
ML 179
Synonym:
3-Cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione
Molecular Formula:
C21H25F3N4O2
Physical Form:
Crystalline Solid
Purity:
>99%
CAS:
1883548-87-5
Solubility:
Soluble to 50mM in DMSO
Formula Weight:
422.44
Product Type:
Bioactive Small Molecule
Chemical Name or Material: TC-G 1005
Synonym: (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone
Molecular Formula: C25H25N3O2
Physical Form: Solid
Purity: >98%
CAS: 1415407-60-1
Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight: 399.48
Product Type: Bioactive Small Molecule
Chemical Name or Material:
TC-G 1005
Synonym:
(4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone
Molecular Formula:
C25H25N3O2
Physical Form:
Solid
Purity:
>98%
CAS:
1415407-60-1
Solubility:
Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight:
399.48
Product Type:
Bioactive Small Molecule