7082165

Tocris Bioscience™ NS 8593 Hydrochloride

Selective negative modulator of KCa2 (SK) channels; inhibits SK currents

Manufacturer: Fischer Scientific

CAS Number: 875755-24-1

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Chemical Name or Material

NS 8593 hydrochloride

Synonym

N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride

Molecular Formula

C17H17N3·HCl

Physical Form

Solid

Purity

>98%

CAS

875755-24-1

Solubility

Soluble to 100mM in DMSO and to 20mM in ethanol

Formula Weight

299.8

Product Type

Bioactive Small Molecule

Other Options

Image Product Name Manufacturer Price Range
459710
Tocris Bioscience™ NS 8593 Hydrochloride
Fischer Scientific ₹ 26,780.28
459750
Tocris Bioscience™ NS 8593 Hydrochloride
Fischer Scientific ₹ 1,07,976.72
50-202-9674
Medchemexpress LLC HY-110105 5mg Medchemexpress, NS8593 (hydrochloride) CAS:875755-24-1 Purity:>98%
Medchemexpress LLC ₹ 9,882.18
CS-0032958
NS8593 (hydrochloride)
ChemScene ₹ 10,267.20 - ₹ 41,068.80
AD92236
875755-24-1 | NS8593 hydrochloride
A2B Chem ₹ 2,310.12 - ₹ 32,085.00

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Description

  • Selective KCa2 (SK) channel negative modulator; inhibits SK channel currents (Kd values are 0.42, 0.6 and 0.73 μM for SK1, SK2 and SK3 respectively at 0.5 μM Ca2+)
  • Exhibits selectivity for SK channels over KCa1.1 (BK), KCa3.1 (IK), Kv, Nav and Cav channels
  • Inhibits afterhyperpolarization in hippocampal slices.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C

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Chemical Name or Material:
NS 8593 hydrochloride

Synonym:
N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride

Molecular Formula:
C17H17N3·HCl

Physical Form:
Solid

Purity:
>98%

CAS:
875755-24-1

Solubility:
Soluble to 100mM in DMSO and to 20mM in ethanol

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299.8

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Bioactive Small Molecule

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