7082165
Tocris Bioscience™ NS 8593 Hydrochloride
Selective negative modulator of KCa2 (SK) channels; inhibits SK currents
Manufacturer: Fischer Scientific
CAS Number: 875755-24-1
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Chemical Name or Material
NS 8593 hydrochloride
Synonym
N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride
Molecular Formula
C17H17N3·HCl
Physical Form
Solid
Purity
>98%
CAS
875755-24-1
Solubility
Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight
299.8
Product Type
Bioactive Small Molecule
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ NS 8593 Hydrochloride | -- | ₹ 27,857.00 | ||
Tocris Bioscience™ NS 8593 Hydrochloride | -- | ₹ 1,12,318.00 | ||
Medchemexpress LLC HY-110105 5mg Medchemexpress, NS8593 (hydrochloride) CAS:875755-24-1 Purity:>98% | -- | ₹ 10,279.50 | ||
NS8593 (hydrochloride) | -- | ₹ 10,680.00 - ₹ 42,720.00 | ||
875755-24-1 | NS8593 hydrochloride | -- | ₹ 2,403.00 - ₹ 33,375.00 |
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Description
- Selective KCa2 (SK) channel negative modulator; inhibits SK channel currents (Kd values are 0.42, 0.6 and 0.73 μM for SK1, SK2 and SK3 respectively at 0.5 μM Ca2+)
- Exhibits selectivity for SK channels over KCa1.1 (BK), KCa3.1 (IK), Kv, Nav and Cav channels
- Inhibits afterhyperpolarization in hippocampal slices.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C