7110797

Tocris Bioscience™ BAZ2-ICR

Selective BAZ2 inhibitor

Manufacturer: Fischer Scientific

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Chemical Name or Material

4-[4-(1-Methyl-1H-pyrazole-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]benzonitrile

Molecular Formula

C20H19N7

Purity

>98%

Target

Bromodomain Inhibitors

Formula Weight

357.41

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Description

  • Selective BAZ2 bromodomain inhibitor (IC50 values are 130 and 180 nM for BAZ2A and BAZ2B respectively)
  • Exhibits 15-fold selectivity for the BAZ2 bromodomain over the CERC2 bromodomain and >100-fold selectivity over a range of other bromodomains
  • Accelerates FRAP recovery in a BAZ2A FRAP assay.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C