7110913
Tocris Bioscience™ PF CBP1
Selective CBP/p300 bromodomain inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1962928-21-7
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Chemical Name or Material
5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole
Target
Bromodomain Inhibitors
Formula Weight
488.62
CAS
1962928-21-7
Molecular Formula
C29H36N4O3
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ PF CBP1 | Fischer Scientific | -- | |
| | Tocris Bioscience™ PF CBP1 | Fischer Scientific | -- | |
 | 5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole | Aaron Chemicals LLC | ₹ 13,528.00 - ₹ 75,561.00 | |
 | 1962928-21-7 | 5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole | A2B Chem | ₹ 4,895.00 - ₹ 64,881.00 |
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Description
- Selective CBP/p300 bromodomain inhibitor (IC50 values are 125 and 363 nM, respectively)
- Exhibits >100-fold selectivity for CBP over BRD4
- Also exhibits selectivity over a panel of other bromodomains
- Reduces LPS-induced IL-1β , IL-6 and IFN-β expression in macrophages in vitro
- Also downregulates RGS4 expression in primary cortical neurons in vitro
- Negative Control also available.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
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Chemical Name or Material: 5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole
Target: Bromodomain Inhibitors
Formula Weight: 488.62
CAS: 1962928-21-7
Molecular Formula: C29H36N4O3
Purity: >98%
Chemical Name or Material:
5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole
Target:
Bromodomain Inhibitors
Formula Weight:
488.62
CAS:
1962928-21-7
Molecular Formula:
C29H36N4O3
Purity:
>98%
Chemical Name or Material: [3-[4-[2-[5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-1H-1,3-benzodiazol-2-yl]ethyl]phenoxy]propyl]dimethylamine
Target: Bromodomain Inhibitors
Formula Weight: 531.69
CAS: 1962928-22-8
Molecular Formula: C31H41N5O3
Purity: >98%
Chemical Name or Material:
[3-[4-[2-[5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-1H-1,3-benzodiazol-2-yl]ethyl]phenoxy]propyl]dimethylamine
Target:
Bromodomain Inhibitors
Formula Weight:
531.69
CAS:
1962928-22-8
Molecular Formula:
C31H41N5O3
Purity:
>98%
Chemical Name or Material: N-Butyl-1H-benzimidazol-2-amine hydrochloride
Target: TRPC Channel Blockers
Formula Weight: 225.72
CAS: 1992047-63-8
Molecular Formula: C11H15N3.HCl
Purity: >99%
Chemical Name or Material:
N-Butyl-1H-benzimidazol-2-amine hydrochloride
Target:
TRPC Channel Blockers
Formula Weight:
225.72
CAS:
1992047-63-8
Molecular Formula:
C11H15N3.HCl
Purity:
>99%
Chemical Name or Material: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
Target: Retinoid X Receptor Agonists
Formula Weight: 348.48
CAS: 153559-49-0
Molecular Formula: C24H28O2
Purity: >99%
Chemical Name or Material:
4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
Target:
Retinoid X Receptor Agonists
Formula Weight:
348.48
CAS:
153559-49-0
Molecular Formula:
C24H28O2
Purity:
>99%