7110832

Tocris Bioscience™ CGP 60474

Potent cdk inhibitor

Manufacturer: Fischer Scientific

CAS Number: 164658-13-3

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Chemical Name or Material

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol

Target

Cyclin-dependent Kinase Inhibitors

Formula Weight

355.82

CAS

164658-13-3

Molecular Formula

C18H18ClN5O

Purity

>98%

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ CGP 60474
-- ₹ 21,783.64
Tocris Bioscience™ CGP 60474
-- ₹ 90,954.44
eMolecules​ Cgp-60474 | 164658-13-3 | MFCD00938945 | 50mg
-- ₹ 43,896.58
Medchemexpress LLC HY-11009 10mg , CGP60474 CAS:164658-13-3 Purity:>98%
-- ₹ 12,148.50
164658-13-3 | 1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-
-- ₹ 2,581.00 - ₹ 46,725.00

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Description

  • Potent cyclin-dependent kinase (cdk) inhibitor (reported IC50 values are 3 - 80, 9.5, 13, 17 - 60, 200 and 220 nM for cdk2, cdk5, cdk9, cdk1, cdk4 and cdk7, respectively)
  • Also inhibits PKCα in the low micromolar range
  • Displays reversible G1/S cell cycle arrest in U2-OS cells.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C