7110850
Tocris Bioscience™ HTH 01-015
Potent and selective NUAK1 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1613724-42-7
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Chemical Name or Material
5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one
Target
Other Kinase Inhibitors
Formula Weight
468.55
CAS
1613724-42-7
Molecular Formula
C26H28N8O
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ HTH 01-015 | Fischer Scientific | ₹ 25,110.15 | |
| | Tocris Bioscience™ HTH 01-015 | Fischer Scientific | ₹ 1,02,624.09 | |
 | Selleck Chemical LLC HTH-01-015 5mg 1613724-42-7 | Selleck Chemical LLC | ₹ 9,959.18 | |
 | Sigma Aldrich Fine Chemicals Biosciences HTH-01-015 >=98% (HPLC) | 1613724-42-7 | MFCD28167816 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 14,044.67 |
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Description
- Potent and selective NUAK1 inhibitor (IC50 = 100 nM)
- Exhibits no significant inhibition against a panel of 139 kinases, including ten AMPK family members
- Inhibits NUAK1-mediated MYPT1 phosphorylation
- Also inhibits cell proliferation in U2OS cells in vitro , to a similar extent as NUAK1 knockdown models.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one
Target: Other Kinase Inhibitors
Formula Weight: 468.55
CAS: 1613724-42-7
Molecular Formula: C26H28N8O
Purity: >98%
Chemical Name or Material:
5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one
Target:
Other Kinase Inhibitors
Formula Weight:
468.55
CAS:
1613724-42-7
Molecular Formula:
C26H28N8O
Purity:
>98%
Chemical Name or Material: 2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide
Target: Lipid Metabolism Inhibitors
Formula Weight: 494.35
CAS: 1267610-30-9
Molecular Formula: C20H17Cl2N5O4S
Purity: >99%
Chemical Name or Material:
2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide
Target:
Lipid Metabolism Inhibitors
Formula Weight:
494.35
CAS:
1267610-30-9
Molecular Formula:
C20H17Cl2N5O4S
Purity:
>99%
Chemical Name or Material: 4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid
Target: Ubiquitin Ligase (E3) Inhibitors
Formula Weight: 466.46
CAS: 916232-21-8
Molecular Formula: C28H19FN2O4
Purity: >98%
Chemical Name or Material:
4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid
Target:
Ubiquitin Ligase (E3) Inhibitors
Formula Weight:
466.46
CAS:
916232-21-8
Molecular Formula:
C28H19FN2O4
Purity:
>98%
Chemical Name or Material: N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide
Target: ASK1 Inhibitors
Formula Weight: 362.31
CAS: 1124381-43-6
Molecular Formula: C16H13F3N6O
Purity: >98%
Chemical Name or Material:
N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide
Target:
ASK1 Inhibitors
Formula Weight:
362.31
CAS:
1124381-43-6
Molecular Formula:
C16H13F3N6O
Purity:
>98%