7110850
Tocris Bioscience™ HTH 01-015
Potent and selective NUAK1 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1613724-42-7
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Chemical Name or Material
5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one
Target
Other Kinase Inhibitors
Formula Weight
468.55
CAS
1613724-42-7
Molecular Formula
C26H28N8O
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ HTH 01-015 | -- | ₹ 26,119.72 | ||
Tocris Bioscience™ HTH 01-015 | -- | ₹ 1,06,750.16 | ||
Selleck Chemical LLC HTH-01-015 5mg 1613724-42-7 | -- | ₹ 10,359.60 | ||
Sigma Aldrich Fine Chemicals Biosciences HTH-01-015 >=98% (HPLC) | 1613724-42-7 | MFCD28167816 | 5MG | -- | ₹ 14,609.35 |
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Description
- Potent and selective NUAK1 inhibitor (IC50 = 100 nM)
- Exhibits no significant inhibition against a panel of 139 kinases, including ten AMPK family members
- Inhibits NUAK1-mediated MYPT1 phosphorylation
- Also inhibits cell proliferation in U2OS cells in vitro , to a similar extent as NUAK1 knockdown models.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C