7110858

Tocris Bioscience™ MSC 2032964A

Potent and selective ASK1 inhibitor; orally bioavailable

Manufacturer: Fischer Scientific

CAS Number: 1124381-43-6

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Chemical Name or Material

N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide

Target

ASK1 Inhibitors

Formula Weight

362.31

CAS

1124381-43-6

Molecular Formula

C16H13F3N6O

Purity

>98%

Other Options

Image Product Name Manufacturer Price Range
56-411-0
Tocris Bioscience™ MSC 2032964A
Fischer Scientific ₹ 27,892.56
56-415-0
Tocris Bioscience™ MSC 2032964A
Fischer Scientific ₹ 1,08,318.96
AE28490
1124381-43-6 | Msc 2032964a
A2B Chem ₹ 5,048.04 - ₹ 52,277.16

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Description

  • Potent and selective ASK1 inhibitor (IC50 = 93 nM)
  • Selective for ASK1 over a panel of 210 kinases
  • Blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes
  • Suppresses neuroinflammation in a mouse EAE model
  • Orally bioavailable and brain penetrant.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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7110858

Potent and selective ASK1 inhibitor...


Chemical Name or Material:
N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide

Target:
ASK1 Inhibitors

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362.31

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1124381-43-6

Molecular Formula:
C16H13F3N6O

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