7110871
Tocris Bioscience™ GW 2580
Selective cFMS kinase inhibitor; orally bioavailable
Manufacturer: Fischer Scientific
CAS Number: 870483-87-7
The price for this product is unavailable. Please request a quote
Chemical Name or Material
5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Target
Additional RTK Inhibitors
Formula Weight
366.41
CAS
870483-87-7
Molecular Formula
C20H22N4O3
Purity
>99%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ GW 2580 | Fischer Scientific | ₹ 18,951.54 | |
| | Tocris Bioscience™ GW 2580 | Fischer Scientific | ₹ 78,715.20 | |
| | MilliporeSigma™ Calbiochem™ cFMS Receptor Tyrosine Kinase Inhibitor | MilliporeSigma™ | ₹ 14,313.33 | |
 | Medchemexpress LLC HY-10917 1g , GW2580 CAS:870483-87-7 Purity:98% | Medchemexpress LLC | ₹ 52,195.88 | |
 | Sigma Aldrich Fine Chemicals Biosciences GW2580 >=98% (HPLC) | 870483-87-7 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 44,046.29 | |
 | Sigma Aldrich Fine Chemicals Biosciences GW2580 >=98% (HPLC) | 870483-87-7 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 11,109.97 | |
 | eMolecules GW2580 | 870483-87-7 | MFCD12024701 | 1g | eMolecules | ₹ 53,090.84 | |
 | Medchemexpress LLC HY-10917 10mg Medchemexpress, GW2580 CAS:870483-87-7 Purity:>98% | Medchemexpress LLC | ₹ 7,726.07 |
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Description
- Potent and selective cFMS kinase inhibitor (IC50 = 0.06 μM)
- Exhibits selectivity for cFMS kinase over 186 other kinases
- Inhibits CSF-1-induced growth of rat monocytes in vitro
- Also inhibits bone resorption in osteoclast cultures, as well as connective tissue and bone destruction in a rat adjuvant arthritis model
- Suppresses M-NFS-60 tumor cell growth in mice
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Target: Additional RTK Inhibitors
Formula Weight: 366.41
CAS: 870483-87-7
Molecular Formula: C20H22N4O3
Purity: >99%
Chemical Name or Material:
5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Target:
Additional RTK Inhibitors
Formula Weight:
366.41
CAS:
870483-87-7
Molecular Formula:
C20H22N4O3
Purity:
>99%
Chemical Name or Material: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid
Target: PPAR delta Receptor Agonists
Formula Weight: 453.5
CAS: 317318-70-0
Molecular Formula: C21H18F3NO3S2
Purity: >98%
Chemical Name or Material:
2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid
Target:
PPAR delta Receptor Agonists
Formula Weight:
453.5
CAS:
317318-70-0
Molecular Formula:
C21H18F3NO3S2
Purity:
>98%
Chemical Name or Material: N-[4-[[4-(1-Methylethyl)-1-piperazinyl]sulfonyl]phenyl]-2-nitro-4-(trifluoromethyl)benzamide hydrochloride
Target: TRPV Antagonists
Formula Weight: 536.95
CAS: 2109450-40-8
Molecular Formula: C21H23F3N4O5S.HCl
Purity: >99%
Chemical Name or Material:
N-[4-[[4-(1-Methylethyl)-1-piperazinyl]sulfonyl]phenyl]-2-nitro-4-(trifluoromethyl)benzamide hydrochloride
Target:
TRPV Antagonists
Formula Weight:
536.95
CAS:
2109450-40-8
Molecular Formula:
C21H23F3N4O5S.HCl
Purity:
>99%
Chemical Name or Material: N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate
Target: VEGF Receptor Inhibitors
Formula Weight: 464.9
CAS: 212142-18-2
Molecular Formula: C20H15ClN4.C4H6O4
Purity: >99%
Chemical Name or Material:
N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate
Target:
VEGF Receptor Inhibitors
Formula Weight:
464.9
CAS:
212142-18-2
Molecular Formula:
C20H15ClN4.C4H6O4
Purity:
>99%