7110907

Tocris Bioscience™ A 425619

Potent TRPV1 antagonist

Manufacturer: Fischer Scientific

CAS Number: 581809-67-8

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Chemical Name or Material

N-5-Isoquinolinyl-N′-[[(4-(trifluoromethyl)phenyl]methyl]urea

Target

TRPV Antagonists

Formula Weight

345.32

CAS

581809-67-8

Molecular Formula

C18H14F3N3O

Purity

>98%

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ A 425619
-- ₹ 27,545.50
Tocris Bioscience™ A 425619
-- ₹ 1,14,543.00
A-425619
-- ₹ 12,638.00 - ₹ 1,51,300.00
581809-67-8 | 1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA
-- ₹ 5,518.00 - ₹ 58,473.00

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Description

  • Potent TRPV1 antagonist (IC50 = 3-9 nM)
  • Blocks capsaicin-evoked currents in rat DRG neurons and inhibits TRPV1-activation by anandamide (Cat
  • No
  • 1339) and N -arachidonoyl-dopamine
  • Reduces pain in inflammatory, postoperative and osteoarthritic in vivo pain models.

SAFETY INFORMATION

  • Recommended Storage : Store at Room Temperature