7114682
Tocris Bioscience™ JNJ 55511118
Selective, high affinity negative modulator of AMPA receptors containing TARP-γ8
Manufacturer: Fischer Scientific
CAS Number: 2036081-86-2
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Chemical Name or Material
5-[2-Chloro-6-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-benzimidazol-2-one
Assay Percent Range
>98%
Formula Weight
Observed MW: 328.67
CAS
2036081-86-2
Molecular Formula
C14H8ClF3N2O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ JNJ 55511118 | Fischer Scientific | ₹ 47,015.22 | |
| | Tocris Bioscience™ JNJ 55511118 | Fischer Scientific | ₹ 11,336.70 | |
 | 2036081-86-2 | JNJ55511118 | A2B Chem | ₹ 2,481.24 - ₹ 45,517.92 |
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Description
- High affinity and selective negative modulator of AMPA receptors containing TARP-γ8 (Ki = 26 nM)
- Exhibits <50% binding against a panel of 52 receptors, ion channels and transporters (except 5HT2B and melatonin receptors 78% and 57%, respectively)
- Also displays minimal activity against other TARP-less AMPARs and AMPARs coexpressed with other TARPs or CNIH2
- Orally bioavailable and brain penetrant
- Anticonvulsant.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
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Chemical Name or Material: 5-[2-Chloro-6-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-benzimidazol-2-one
Assay Percent Range: >98%
Formula Weight: Observed MW: 328.67
CAS: 2036081-86-2
Molecular Formula: C14H8ClF3N2O2
Chemical Name or Material:
5-[2-Chloro-6-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-benzimidazol-2-one
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 328.67
CAS:
2036081-86-2
Molecular Formula:
C14H8ClF3N2O2
Chemical Name or Material: 1-[[2-[2-(4-Bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazole hydrochloride
Assay Percent Range: >98%
Formula Weight: Observed MW: 373.67
CAS: 939825-12-4
Molecular Formula: C15H17BrN2O2.HCl
Chemical Name or Material:
1-[[2-[2-(4-Bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazole hydrochloride
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 373.67
CAS:
939825-12-4
Molecular Formula:
C15H17BrN2O2.HCl
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