7121041
Tocris Bioscience™ PF 06409577
Potent and selective allosteric activator of AMPK
Manufacturer: Fischer Scientific
CAS Number: 1467057-23-3
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Chemical Name or Material
PF 06409577
Synonym
6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid
Molecular Formula
C19H16ClNO3
Physical Form
Solid
Product Type
Bioactive Small Molecule
CAS
1467057-23-3
Solubility
Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight
341.79
Color
Gray
Purity
99%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ PF 06409577 | Fischer Scientific | ₹ 91,891.44 | |
| | Tocris Bioscience™ PF 06409577 | Fischer Scientific | ₹ 22,887.30 | |
 | Sigma Aldrich Fine Chemicals Biosciences PF-06409577 | 1467057-23-3 | MFCD29917835 | 25mg | Sigma Aldrich Fine Chemicals Biosciences | ₹ 45,894.38 | |
 | 1H-Indole-3-carboxylic acid, 6-chloro-5-[4-(1-hydroxycyclobutyl)phenyl]- | Aaron Chemicals LLC | ₹ 941.16 - ₹ 34,480.68 |
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Description
- Potent and selective allosteric activator of AMPK (EC50 values are 7 and >40000 nM for AMPKα1β1γ1 and AMPKα1β2γ1, respectively)
- Exhibits minimal off-target effects on a panel of receptors, ion channels, PDEs and kinases
- Improves kidney function and reduces proteinuria in a preclinical model of diabetic nephropathy
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at Room Temperature
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Chemical Name or Material: PF 06409577
Synonym: 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid
Molecular Formula: C19H16ClNO3
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 1467057-23-3
Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight: 341.79
Color: Gray
Purity: 99%
Chemical Name or Material:
PF 06409577
Synonym:
6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid
Molecular Formula:
C19H16ClNO3
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
1467057-23-3
Solubility:
Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight:
341.79
Color:
Gray
Purity:
99%
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