7121012
Tocris Bioscience™ Ex 26
Potent and selective S1P1 receptor antagonist
Manufacturer: Fischer Scientific
CAS Number: 144678-63-7
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Chemical Name or Material
1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid
Solubility
Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight
494.98
Color
White
Purity
>98%
CAS
144678-63-7
Molecular Formula
C28H28ClFN2O3
Physical Form
Solid
Product Type
Bioactive Small Molecule
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Ex 26 | Fischer Scientific | ₹ 97,025.04 | |
| | Tocris Bioscience™ Ex 26 | Fischer Scientific | ₹ 23,272.32 | |
 | Tocris Bioscience™ NSC 668036 | Fischer Scientific | -- | |
| | Tocris Bioscience™ NSC 668036 | Fischer Scientific | ₹ 19,978.26 | |
| | Tocris Bioscience™ NSC 668036 | Fischer Scientific | ₹ 83,806.02 | |
 | 144678-63-7 | (2S)-N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanyl-2-hydroxy-3-methyl-butanoicAcid | A2B Chem | ₹ 2,909.04 - ₹ 30,630.48 |
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Description
- Potent and selective S1P1 receptor antagonist (IC50 = 0.93 nM)
- Exhibits > 3,000-fold selectivity for S1P1 over S1P2, S1P3, S1P4 and S1P5
- Induces lymphocyte sequestration in peripheral lymph nodes and upregulates S1P1 receptor expression
- Reduces disease severity in mice with EAE
- Increases IFN-α production in stimulated dendritic cells in vivo .
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
Show Difference
Chemical Name or Material: 1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid
Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight: 494.98
Color: White
Purity: >98%
CAS: 144678-63-7
Molecular Formula: C28H28ClFN2O3
Physical Form: Solid
Product Type: Bioactive Small Molecule
Chemical Name or Material:
1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid
Solubility:
Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight:
494.98
Color:
White
Purity:
>98%
CAS:
144678-63-7
Molecular Formula:
C28H28ClFN2O3
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
Chemical Name or Material: 8-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]methyl]-3,7-dihydro-1,3-dimethyl-7-(3-methylbutyl)-1H-purine-2,6-dione hydrochloride
Solubility: Soluble to 100mM in water and to 100mM in DMSO
Formula Weight: 452.98
Color: White
Purity: >98%
CAS: 1307896-46-3
Molecular Formula: C21H32N6O3.HCl
Physical Form: Solid
Product Type: Bioactive Small Molecule
Chemical Name or Material:
8-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]methyl]-3,7-dihydro-1,3-dimethyl-7-(3-methylbutyl)-1H-purine-2,6-dione hydrochloride
Solubility:
Soluble to 100mM in water and to 100mM in DMSO
Formula Weight:
452.98
Color:
White
Purity:
>98%
CAS:
1307896-46-3
Molecular Formula:
C21H32N6O3.HCl
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
Chemical Name or Material: N-[(1 R,3 S,5 S)-9-(2-((2-Chlorophenyl)amino)-2-exoethyl)-9-azabicyclo[3.3.1 ]nonan-3-yl)-3,4,5-trimethoxybenzamide
Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight: 502
Color: White
Purity: 98%
CAS: 2080300-49-6
Molecular Formula: C26H32ClN3O5
Physical Form: Solid
Product Type: Bioactive Small Molecule
Chemical Name or Material:
N-[(1 R,3 S,5 S)-9-(2-((2-Chlorophenyl)amino)-2-exoethyl)-9-azabicyclo[3.3.1 ]nonan-3-yl)-3,4,5-trimethoxybenzamide
Solubility:
Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight:
502
Color:
White
Purity:
98%
CAS:
2080300-49-6
Molecular Formula:
C26H32ClN3O5
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
Chemical Name or Material: (E)-4-Methyl-5-(((phenylsulfonyl)oxy)imino)-[1,1'-bi(cyclohexane)]-3,6-dien-2-one
Solubility: Soluble to 50mM in DMSO
Formula Weight: 359.44
Color: White
Purity: >98%
CAS: 143621-35-6
Molecular Formula: C19H21NO4S
Physical Form: Solid
Product Type: Bioactive Small Molecule
Chemical Name or Material:
(E)-4-Methyl-5-(((phenylsulfonyl)oxy)imino)-[1,1'-bi(cyclohexane)]-3,6-dien-2-one
Solubility:
Soluble to 50mM in DMSO
Formula Weight:
359.44
Color:
White
Purity:
>98%
CAS:
143621-35-6
Molecular Formula:
C19H21NO4S
Physical Form:
Solid
Product Type:
Bioactive Small Molecule