7121034
Tocris Bioscience™ CZC 25146
Potent LRRK2 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1191911-26-8
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Chemical Name or Material
CZC 25146
Synonym
N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide
Molecular Formula
C22H25FN6O4S
Physical Form
Solid
Product Type
Bioactive Small Molecule
CAS
1191911-26-8
Solubility
Soluble to 100mM in DMSO
Formula Weight
488.54
Color
Pale-purple
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ CZC 25146 | Fischer Scientific | ₹ 28,980.88 | |
| | Tocris Bioscience™ CZC 25146 | Fischer Scientific | ₹ 1,21,779.26 | |
 | Medchemexpress LLC HY-15800A 5mg Medchemexpress, CZC-25146 CAS:1191911-26-8 Purity:>98% | Medchemexpress LLC | ₹ 7,905.74 |
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Description
- Potent LRRK2 inhibitor (IC50 values are 4.76 and 6.87 nM for for wild-type and G2019S mutant forms of LRRK2, respectively)
- Also inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2
- Attenuates mutant LRRK2-induced injury of cultured rodent and human neurons
- Cell permeable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: CZC 25146
Synonym: N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide
Molecular Formula: C22H25FN6O4S
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 1191911-26-8
Solubility: Soluble to 100mM in DMSO
Formula Weight: 488.54
Color: Pale-purple
Purity: >98%
Chemical Name or Material:
CZC 25146
Synonym:
N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide
Molecular Formula:
C22H25FN6O4S
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
1191911-26-8
Solubility:
Soluble to 100mM in DMSO
Formula Weight:
488.54
Color:
Pale-purple
Purity:
>98%
Chemical Name or Material: AMG 837 hemicalcium salt
Synonym: (βS)-β-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic acid hemicalcium salt
Molecular Formula: C26H20F3O3.?Ca
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 1291087-14-3
Solubility: Soluble to 100mM in DMSO
Formula Weight: 457.47
Color: White
Purity: >98%
Chemical Name or Material:
AMG 837 hemicalcium salt
Synonym:
(βS)-β-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic acid hemicalcium salt
Molecular Formula:
C26H20F3O3.?Ca
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
1291087-14-3
Solubility:
Soluble to 100mM in DMSO
Formula Weight:
457.47
Color:
White
Purity:
>98%
Chemical Name or Material: Ethyl 5-cyano-2-methyl-6-[4-[[[(phenylmethyl)sulfonyl]amino]carbonyl]-1-piperidinyl]-3-pyridinecarboxylate
Synonym: Ethyl 5-cyano-2-methyl-6-[4-[[[(phenylmethyl)sulfonyl]amino]carbonyl]-1-piperidinyl]-3-pyridinecarboxylate
Molecular Formula: C23H26N4O5S
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 919351-41-0
Solubility: Soluble to 100mM in DMSO
Formula Weight: 470.54
Color: White
Purity: 98%
Chemical Name or Material:
Ethyl 5-cyano-2-methyl-6-[4-[[[(phenylmethyl)sulfonyl]amino]carbonyl]-1-piperidinyl]-3-pyridinecarboxylate
Synonym:
Ethyl 5-cyano-2-methyl-6-[4-[[[(phenylmethyl)sulfonyl]amino]carbonyl]-1-piperidinyl]-3-pyridinecarboxylate
Molecular Formula:
C23H26N4O5S
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
919351-41-0
Solubility:
Soluble to 100mM in DMSO
Formula Weight:
470.54
Color:
White
Purity:
98%
Chemical Name or Material: Perifosine
Synonym: Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate
Molecular Formula: C25H52NO4P
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 157716-52-4
Solubility: Soluble to 100mM in water and to 100mM in ethanol
Formula Weight: 461.66
Color: White
Purity: >98%
Chemical Name or Material:
Perifosine
Synonym:
Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate
Molecular Formula:
C25H52NO4P
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
157716-52-4
Solubility:
Soluble to 100mM in water and to 100mM in ethanol
Formula Weight:
461.66
Color:
White
Purity:
>98%