556710
Tocris Bioscience™ EPZ 004777
Manufacturer: Tocris Bioscience™
CAS Number: 1338466-77-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 556710-Each-of-1 | In Stock | ₹ 36,534.50 |
556710 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,534.50
GST (18%): ₹ 6,576.21
Total Price: ₹ 43,110.71
Chemical Name or Material
EPZ 004777
Synonym
7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Solubility
Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight
539.67
Product Type
Bioactive Small Molecule
CAS
1338466-77-5
Quantity
10 mg
Molecular Formula
C28H41N7O4
Physical Form
Solid
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | MilliporeSigma™ Calbiochem™ DOT1L Inhibitor, EPZ004777 | MilliporeSigma™ | ₹ 24,119.00 | |
 | 1338466-77-5 | Epz004777 | A2B Chem | ₹ 12,905.00 - ₹ 1,02,528.00 |
Related Products
Description
- EPZ 004777 is a highly potent DOT1L inhibitor (IC50 = 0.4 nM)
- Exhibits >1000-fold selectivity for DOT1L over a panel of other methyltransferases
- Selectively inhibits proliferation and induces apoptosis of MLL -rearranged cells in vitro
- Prolongs survival in a MLL xenograft mouse model
- Enhances efficiency of Yamanaka-factor factor reprogramming of fibroblasts by 3-4-fold.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: EPZ 004777
Synonym: 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight: 539.67
Product Type: Bioactive Small Molecule
CAS: 1338466-77-5
Quantity: 10 mg
Molecular Formula: C28H41N7O4
Physical Form: Solid
Purity: >98%
Chemical Name or Material:
EPZ 004777
Synonym:
7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Solubility:
Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight:
539.67
Product Type:
Bioactive Small Molecule
CAS:
1338466-77-5
Quantity:
10 mg
Molecular Formula:
C28H41N7O4
Physical Form:
Solid
Purity:
>98%
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