7121024
Tocris Bioscience™ PF 3758309 dihydrochloride
Potent PAK4 inhibitor; orally available
Manufacturer: Fischer Scientific
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Chemical Name or Material
PF 3758309 Dihydrochloride
Solubility
Soluble to 100mM in water and to 100mM in DMSO
Formula Weight
563.55
Color
Off-white
Purity
>98%
Synonym
N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide dihydrochloride
Molecular Formula
C25H30N8OS.2HCl
Physical Form
Solid
Product Type
Bioactive Small Molecule
Related Products
Description
- Potent PAK4 inhibitor (IC50 = 1.3 nM; Kd = 2.7 nM)
- Inhibits proliferation and anchorage-independent growth of a panel of tumor cell lines in vitro
- Suppresses growth of human HCT116 and A549 tumor cell xenografts in mice
- Orally available.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: PF 3758309 Dihydrochloride
Solubility: Soluble to 100mM in water and to 100mM in DMSO
Formula Weight: 563.55
Color: Off-white
Purity: >98%
Synonym: N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide dihydrochloride
Molecular Formula: C25H30N8OS.2HCl
Physical Form: Solid
Product Type: Bioactive Small Molecule
Chemical Name or Material:
PF 3758309 Dihydrochloride
Solubility:
Soluble to 100mM in water and to 100mM in DMSO
Formula Weight:
563.55
Color:
Off-white
Purity:
>98%
Synonym:
N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide dihydrochloride
Molecular Formula:
C25H30N8OS.2HCl
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
Chemical Name or Material: TP 064
Solubility: Soluble to 100mM in 1eq. HCl and to 100mM in DMSO
Formula Weight: 458.6
Color: White
Purity: >98%
Synonym: N-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide
Molecular Formula: C28H34N4O2
Physical Form: Solid
Product Type: Bioactive Small Molecule
Chemical Name or Material:
TP 064
Solubility:
Soluble to 100mM in 1eq. HCl and to 100mM in DMSO
Formula Weight:
458.6
Color:
White
Purity:
>98%
Synonym:
N-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide
Molecular Formula:
C28H34N4O2
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
Chemical Name or Material: FRAX 597
Solubility: Soluble to 20mM in DMSO
Formula Weight: 558.1
Color: Yellow
Purity: >98%
Synonym: 6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Molecular Formula: C29H28ClN7OS
Physical Form: Solid
Product Type: Bioactive Small Molecule
Chemical Name or Material:
FRAX 597
Solubility:
Soluble to 20mM in DMSO
Formula Weight:
558.1
Color:
Yellow
Purity:
>98%
Synonym:
6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Molecular Formula:
C29H28ClN7OS
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
Chemical Name or Material: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Solubility: __
Formula Weight: 479.4
Color: Orange
Purity: 98%
Synonym: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Molecular Formula: C25H22N60.2 HCl
Physical Form: Solid
Product Type: Bioactive Small Molecule
Chemical Name or Material:
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Solubility:
__
Formula Weight:
479.4
Color:
Orange
Purity:
98%
Synonym:
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Molecular Formula:
C25H22N60.2 HCl
Physical Form:
Solid
Product Type:
Bioactive Small Molecule