7121004

Tocris Bioscience™ BRACO 19 trihydrochloride

Telomerase inhibitor

Manufacturer: Fischer Scientific

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Chemical Name or Material

N,N'-[9[[4-(Dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-1-pyrrolidinepropanamide trihydrochloride

Solubility

Soluble to 50 mM in water and to 50 mM in DMSO

Formula Weight

703.14

Color

White

Purity

94%

Synonym

Telomerase inhibitor

Molecular Formula

C35H43N7O2·3HCl

Physical Form

Solid

Product Type

Bioactive Small Molecule

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Description

  • Telomerase inhibitor (IC50 = 115 nM)
  • Inhibits expression of human telomerase reverse transcriptase (hTERT), induces cellular senescence and inhibits growth of uterine cancer cells in vitro
  • Inhibits growth of uterine tumor xenografts in mice.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Fischer Scientific

7121004

Telomerase inhibitor...


Chemical Name or Material:
N,N'-[9[[4-(Dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-1-pyrrolidinepropanamide trihydrochloride

Solubility:
Soluble to 50 mM in water and to 50 mM in DMSO

Formula Weight:
703.14

Color:
White

Purity:
94%

Synonym:
Telomerase inhibitor

Molecular Formula:
C35H43N7O2·3HCl

Physical Form:
Solid

Product Type:
Bioactive Small Molecule

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7121008

Potent and selective LRRK2 inhibito...


Chemical Name or Material:
rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole

Solubility:
Soluble to 50mM in DMSO

Formula Weight:
379.46

Color:
White

Purity:
>98%

Synonym:
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Molecular Formula:
C21H25N5O2

Physical Form:
Solid

Product Type:
Bioactive Small Molecule

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Chemical Name or Material:
7-Chloro-1,3-dihydro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthalenylmethyl)-2H-1,4-benzodiazepin-2-one

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Soluble to 100mM in DMSO and to 100mM in ethanol

Formula Weight:
440.92

Color:
White

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>98%

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Molecular Formula:
C27H21ClN2O2

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Solid

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Bioactive Small Molecule

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Chemical Name or Material:
N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanine-(1S)-1-carboxy-2-methylpropyl ester

Solubility:
Soluble to 100mM in DMSO and to 100mM in ethanol

Formula Weight:
460.52

Color:
White

Purity:
>98%

Synonym:
__

Molecular Formula:
C21H36N2O9

Physical Form:
Solid

Product Type:
Bioactive Small Molecule