7182924
Tocris Bioscience™ KYA 1797K
Wnt/β-catenin signaling inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1956356-56-1
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Chemical Name or Material
(5Z)-5-[[5-(4-Nitrophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid potassium salt
CAS
1956356-56-1
Molecular Formula
C17H11KN2O6S2
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ KYA 1797K | Fischer Scientific | ₹ 36,325.35 | |
| | Tocris Bioscience™ KYA 1797K | Fischer Scientific | ₹ 9,428.71 | |
 | eMolecules Medchem Express / KYA1797K / 5mg / 446256425 / HY-101090 / / 1956356-56-1 / MFCD30718585 / 442.500 / C17H11KN2O6S2 | eMolecules | ₹ 10,579.49 | |
 | Medchemexpress LLC HY-101090 5mg Medchemexpress, KYA1797K CAS:1956356-56-1 Purity:>98% | Medchemexpress LLC | ₹ 6,108.98 | |
 | KYA1797K | ChemScene | ₹ 5,818.08 - ₹ 55,614.00 | |
 | 1956356-56-1 | KYA1797K | A2B Chem | ₹ 1,796.76 - ₹ 13,860.72 |
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Description
- Wnt/β-catenin signaling inhibitor (IC50 = 0.75 μM)
- Increases binding affinity of β-catenin for axin, GSK-3β and β-TrCP
- Promotes formation of the destruction complex, activation of GSK-3β and phosphorylation of β-catenin and K-Ras, leading to their degradation via the ubiquitin/proteasome system
- Reduces levels of β-catenin and K-Ras and inhibits growth of colorectal cancer (CRC) cells in vitro and in mouse xenograft models.
Compare Similar Items
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Chemical Name or Material: (5Z)-5-[[5-(4-Nitrophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid potassium salt
CAS: 1956356-56-1
Molecular Formula: C17H11KN2O6S2
Purity: 98%
Chemical Name or Material:
(5Z)-5-[[5-(4-Nitrophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid potassium salt
CAS:
1956356-56-1
Molecular Formula:
C17H11KN2O6S2
Purity:
98%
Chemical Name or Material: 4-Methyl-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-N-(4-(pyridin-3-yl)phenyl)-1H-pyrrole-2-carboxamide
CAS: 2247732-89-2
Molecular Formula: C26H27N5OS
Purity: 98%
Chemical Name or Material:
4-Methyl-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-N-(4-(pyridin-3-yl)phenyl)-1H-pyrrole-2-carboxamide
CAS:
2247732-89-2
Molecular Formula:
C26H27N5OS
Purity:
98%
Chemical Name or Material: 2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
CAS: 223673-61-8
Molecular Formula: C21H24N4O2S
Purity: 98%
Chemical Name or Material:
2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
CAS:
223673-61-8
Molecular Formula:
C21H24N4O2S
Purity:
98%
Chemical Name or Material: Methyl (Z)-3-[[[4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene]-2-oxoindoline-6-carboxylate
CAS: 656247-17-5
Molecular Formula: C31H33N5O4
Purity: 98%
Chemical Name or Material:
Methyl (Z)-3-[[[4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene]-2-oxoindoline-6-carboxylate
CAS:
656247-17-5
Molecular Formula:
C31H33N5O4
Purity:
98%