7250134
Tocris Bioscience™ SSYA10-001
Potent coronavirus helicase inhibitor; also inhibits human papillomavirus E6
Manufacturer: Fischer Scientific
CAS Number: 675104-49-1
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Chemical Name or Material
2,4-Dihydro-5-[[(2-nitrophenyl)thio]methyl]-4-(2-propen-1-yl)-3 H-1,2,4-triazole-3-thione
Target
Antiviral Compounds
Purity
0.98
CAS
675104-49-1
Molecular Formula
C12H12N4O2S2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ SSYA10-001 | Fischer Scientific | ₹ 40,096.84 | |
| | Tocris Bioscience™ SSYA10-001 | Fischer Scientific | ₹ 1,68,327.32 | |
 | eMolecules Medchem Express / DSHS00884 / 5mg / 527574392 / HY-113794 / / 675104-49-1 / [null] / 308.370 / C12H12N4O2S2 | eMolecules | ₹ 43,313.89 |
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Description
- SSYA10-001 is a potent coronavirus helicase inhibitor (IC50 values are 0.046 μM and >3 μM for unwinding and ATPase, respectively)
- Inhibits SARS-CoV-2 Nsp13 helicase (IC50 = 3.5 μM), blocks dsDNA and dsRNA unwinding activities of Nsp13 (IC50 values are 5.3 μM and 5.7 μM respectively)
- In a SARS-CoV replicon assay SSYA10-001 inhibits (+) sense but not (-) sense RNA synthesis (EC50 = 8.95 μM)
- Also inhibits human papillomavirus E6 (IC50 = 10 μM)
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 2,4-Dihydro-5-[[(2-nitrophenyl)thio]methyl]-4-(2-propen-1-yl)-3 H-1,2,4-triazole-3-thione
Target: Antiviral Compounds
Purity: 0.98
CAS: 675104-49-1
Molecular Formula: C12H12N4O2S2
Chemical Name or Material:
2,4-Dihydro-5-[[(2-nitrophenyl)thio]methyl]-4-(2-propen-1-yl)-3 H-1,2,4-triazole-3-thione
Target:
Antiviral Compounds
Purity:
0.98
CAS:
675104-49-1
Molecular Formula:
C12H12N4O2S2
Chemical Name or Material: (1 R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2 S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1 H)-one
Target: Ras GTPase Inhibitors
Purity: 0.98
CAS: 2252403-56-6
Molecular Formula: C30H30F2N6O3
Chemical Name or Material:
(1 R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2 S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1 H)-one
Target:
Ras GTPase Inhibitors
Purity:
0.98
CAS:
2252403-56-6
Molecular Formula:
C30H30F2N6O3
Chemical Name or Material: N-[2-[[(2 S)-2-Methyl-1-pyrrolidinyl]methyl]-1 H-benzimidazol-6-yl]-6-isoquinolinecarboxamide
Target: Bromodomain Inhibitors
Purity: 0.98
CAS: 2561471-13-2
Molecular Formula: C23H23N5O
Chemical Name or Material:
N-[2-[[(2 S)-2-Methyl-1-pyrrolidinyl]methyl]-1 H-benzimidazol-6-yl]-6-isoquinolinecarboxamide
Target:
Bromodomain Inhibitors
Purity:
0.98
CAS:
2561471-13-2
Molecular Formula:
C23H23N5O
Chemical Name or Material: N-Hydroxy-2,2-dimethyl-N-(phenylmethyl)butanamide
Target: RIP Kinase Inhibitors
Purity: 0.98
CAS: 1956370-21-0
Molecular Formula: C13H19NO2
Chemical Name or Material:
N-Hydroxy-2,2-dimethyl-N-(phenylmethyl)butanamide
Target:
RIP Kinase Inhibitors
Purity:
0.98
CAS:
1956370-21-0
Molecular Formula:
C13H19NO2