75-695-0

Tocris Bioscience™ Verdinexor

Manufacturer: Fischer Scientific

CAS Number: 1392136-43-4

Select a Size

Pack Size SKU Availability Price
Each of 1 75-695-0-Each-of-1 In Stock ₹ 77,613.19

75-695-0 - Each of 1

₹ 77,613.19

In Stock

Quantity

1

Base Price: ₹ 77,613.19

GST (18%): ₹ 13,970.374

Total Price: ₹ 91,583.564

Chemical Name or Material

(2 Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1 H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyridinyl)hydrazide

Quantity

50 mg

Molecular Formula

C18H12F6N6O

CAS

1392136-43-4

Target

Antiviral Compounds

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
7250112
Tocris Bioscience™ Verdinexor
Fischer Scientific --
75-691-0
Tocris Bioscience™ Verdinexor
Fischer Scientific ₹ 18,559.68
50-136-5156
Selleck Chemical LLC Verdinexor (KPT-335) 5mg 1392136-43-4 ATG-527
Selleck Chemical LLC ₹ 20,226.38
50-251-2097
eMolecules​ AstaTech / KPT335 / 5mg / 562547058 / 40840 / 95.000 / 1392136-43-4 / MFCD28167840 / 442.325 / C18H12F6N6O
eMolecules​ ₹ 37,657.52

Related Products

Img

Fischer Scientific

75-691-0

--

Img

Fischer Scientific

7250112

Selective exportin-1 (XPO1/CRM1) in...

Img

Fischer Scientific

77-605-0

--

Img

Fischer Scientific

77-601-0

--

Img

Fischer Scientific

7249492

Selective exportin 1 (XPO1/CRM1) in...

Img

Fischer Scientific

75-545-0

--

Img

Fischer Scientific

75-541-0

--

Img

Fischer Scientific

7250134

Potent coronavirus helicase inhibit...

Description

  • Verdinexor is a selective exportin-1 (XPO1/CRM1) inhibitor
  • It potently inhibits influenza virus ribonucleoprotein (vRNP) export by disrupting XPO1-NEP binding and the replication of influenza virus A and B strains in vitro , including H1N1, H5N1 and H7N9 (IC50 values in the range 40 - 420 nM range)
  • Verdinexor limits influenza A virus spread in mouse lung in vivo
  • In neuroblastoma, verdinexor suppresses cell proliferation and induces cell apoptosis
  • It also induces P53 nuclear accumulation and induces G0/G1 phase cell cycle arrest by activating P53 function
  • Verdinexor inhibits tumor growth in in vivo mouse models
  • Orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

Img

Fischer Scientific

75-695-0

--


Chemical Name or Material:
(2 Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1 H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyridinyl)hydrazide

Quantity:
50 mg

Molecular Formula:
C18H12F6N6O

CAS:
1392136-43-4

Target:
Antiviral Compounds

Purity:
0.98

Img

LIFE TECHNOLOGIES

75-697-6182

--


Chemical Name or Material:
__

Quantity:
100 μg

Molecular Formula:
__

CAS:
__

Target:
__

Purity:
__

Img

LIFE TECHNOLOGIES

75-699-1082

--


Chemical Name or Material:
__

Quantity:
100 μg

Molecular Formula:
__

CAS:
__

Target:
__

Purity:
__

Img

Thermo Scientific™

75-706

--


Chemical Name or Material:
__

Quantity:
25 mL

Molecular Formula:
__

CAS:
__

Target:
Beta-Galactosidase

Purity:
__