7249492
Tocris Bioscience™ Selinexor
Selective exportin 1 (XPO1/CRM1) inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1393477-72-9
The price for this product is unavailable. Please request a quote
Chemical Name or Material
(2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide
CAS
1393477-72-9
Target
Antiviral Compounds
Molecular Formula
C17H11F6N7O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Selinexor | Fischer Scientific | ₹ 19,079.88 | |
| | Tocris Bioscience™ Selinexor | Fischer Scientific | ₹ 79,699.14 | |
 | Selleck Chemical LLC Selinexor (KPT-330) 5mg 1393477-72-9 ATG-010 | Selleck Chemical LLC | ₹ 20,226.38 | |
 | Apexbio Technology LLC KPT-330, 5mg. Cas: 1393477-72-9 MFCD: MFCD27987944. CRM1 inhibitor, orally bioavailable and selective | Apexbio Technology LLC | ₹ 5,818.08 | |
| | eMolecules Ambeed / (Z)-3-(3-(35-Bis(trifluoromethyl)phenyl)-1H-124-triazol-1-yl)-N-(pyrazin-2-yl)acrylohydrazide / 5mg / 552576144 / A140158 / / 1393477-72-9 / MFCD27987944 / 443.313 / C17H11F6N7O | eMolecules | ₹ 5,372.31 | |
| | Selleck Chemical LLC Selinexor (KPT-330) 50mg 1393477-72-9 ATG-010 | Selleck Chemical LLC | ₹ 57,547.66 | |
 | 2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2Z)- | Aaron Chemicals LLC | ₹ 684.48 - ₹ 53,389.44 | |
 | 1393477-72-9 | Kpt-330 | A2B Chem | ₹ 2,310.12 - ₹ 87,442.32 |
Related Products
Description
- Selinexor is an inhibitor of the exportin 1 (XPO1/CRM1) nuclear exporter
- Shows selectivity for TNBC over ER-positive breast cancer cell lines (IC50 values are 11-550 nM and >1000 nM, respectively), and reduces growth of xenografts
- Inhibits growth of thyroid cancer cell lines (IC50 = 150-500 nM), potentiates the anti-tumor effects of Olaparib (Cat
- No
- 7579) in ovarian cancer and breast cancer
- Also a potent inhibitor of SARS-CoV-2 replication in vitro (EC50 = 10 nM) and downregulates the production of pro-inflammatory cytokines including TNF-α and IL-6.
SAFETY INFORMATION
- Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Compare Similar Items
Show Difference
Chemical Name or Material: (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide
CAS: 1393477-72-9
Target: Antiviral Compounds
Molecular Formula: C17H11F6N7O
Chemical Name or Material:
(2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide
CAS:
1393477-72-9
Target:
Antiviral Compounds
Molecular Formula:
C17H11F6N7O
Chemical Name or Material: N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine
CAS: 2083627-02-3
Target: EED
Molecular Formula: C17H15N5O3S
Chemical Name or Material:
N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine
CAS:
2083627-02-3
Target:
EED
Molecular Formula:
C17H15N5O3S
Chemical Name or Material: 3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide
CAS: 612542-14-0
Target: Smoothened
Molecular Formula: C28H26ClF2N3OS
Chemical Name or Material:
3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide
CAS:
612542-14-0
Target:
Smoothened
Molecular Formula:
C28H26ClF2N3OS
Chemical Name or Material: rel-N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]benzamide
CAS: 1035270-39-3
Target: FGF Receptor Inhibitors
Molecular Formula: C26H33N5O3
Chemical Name or Material:
rel-N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]benzamide
CAS:
1035270-39-3
Target:
FGF Receptor Inhibitors
Molecular Formula:
C26H33N5O3