77-605-0

Tocris Bioscience™ Selinexor

Manufacturer: Fischer Scientific

CAS Number: 1393477-72-9

Select a Size

Pack Size SKU Availability Price
Each of 1 77-605-0-Each-of-1 In Stock ₹ 79,699.14

77-605-0 - Each of 1

₹ 79,699.14

In Stock

Quantity

1

Base Price: ₹ 79,699.14

GST (18%): ₹ 14,345.845

Total Price: ₹ 94,044.985

Chemical Name or Material

(2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide

Quantity

50 mg

Molecular Formula

C17H11F6N7O

CAS

1393477-72-9

Target

Antiviral Compounds

Other Options

Image Product Name Manufacturer Price Range
7249492
Tocris Bioscience™ Selinexor
Fischer Scientific --
77-601-0
Tocris Bioscience™ Selinexor
Fischer Scientific ₹ 19,079.88
NC0785745
Selleck Chemical LLC Selinexor (KPT-330) 5mg 1393477-72-9 ATG-010
Selleck Chemical LLC ₹ 20,226.38
50-101-5267
Apexbio Technology LLC KPT-330, 5mg. Cas: 1393477-72-9 MFCD: MFCD27987944. CRM1 inhibitor, orally bioavailable and selective
Apexbio Technology LLC ₹ 5,818.08
50-248-5191
eMolecules​ Ambeed / (Z)-3-(3-(35-Bis(trifluoromethyl)phenyl)-1H-124-triazol-1-yl)-N-(pyrazin-2-yl)acrylohydrazide / 5mg / 552576144 / A140158 / / 1393477-72-9 / MFCD27987944 / 443.313 / C17H11F6N7O
eMolecules​ ₹ 5,372.31
NC0714614
Selleck Chemical LLC Selinexor (KPT-330) 50mg 1393477-72-9 ATG-010
Selleck Chemical LLC ₹ 57,547.66
AR001BHN
2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2Z)-
Aaron Chemicals LLC ₹ 684.48 - ₹ 53,389.44
AA60447
1393477-72-9 | Kpt-330
A2B Chem ₹ 2,310.12 - ₹ 87,442.32

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Description

  • Selinexor is an inhibitor of the exportin 1 (XPO1/CRM1) nuclear exporter
  • Shows selectivity for TNBC over ER-positive breast cancer cell lines (IC50 values are 11-550 nM and >1000 nM, respectively), and reduces growth of xenografts
  • Inhibits growth of thyroid cancer cell lines (IC50 = 150-500 nM), potentiates the anti-tumor effects of Olaparib (Cat
  • No
  • 7579) in ovarian cancer and breast cancer
  • Also a potent inhibitor of SARS-CoV-2 replication in vitro (EC50 = 10 nM) and downregulates the production of pro-inflammatory cytokines including TNF-α and IL-6.

SAFETY INFORMATION

  • Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Compare Similar Items

Show Difference

Img

Fischer Scientific

77-605-0

--


Chemical Name or Material:
(2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide

Quantity:
50 mg

Molecular Formula:
C17H11F6N7O

CAS:
1393477-72-9

Target:
Antiviral Compounds

Img

Fischer Scientific

77-621-0

--


Chemical Name or Material:
N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine

Quantity:
10 mg

Molecular Formula:
C17H15N5O3S

CAS:
2083627-02-3

Target:
EED

Img

Fischer Scientific

77-625-0

--


Chemical Name or Material:
N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine

Quantity:
50 mg

Molecular Formula:
C17H15N5O3S

CAS:
2083627-02-3

Target:
EED

Img

Tocris Bioscience™

77-685

--


Chemical Name or Material:
N-(24-Azido-12,20-dioxo-3,6,9-trioxa-16,17-dithia-13,21-diazatetracosyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

Quantity:
5 mg

Molecular Formula:
C27H48N8O7S3

CAS:
2866429-93-6

Target:
General Laboratory Research Reagent