7199111
Tocris™ JNJ 10198409
Potent PDGFRα and PDGFRβ inhbitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases
Manufacturer: Fischer Scientific
CAS Number: 627518-40-5
The price for this product is unavailable. Please request a quote
Chemical Name or Material
N-(3-Fluorophenyl)-1,4-dihydro-6,7-dimethoxyindeno[1,2-c]pyrazol-3-amine
Target
PDGF Receptor Inhibitors
Purity
98%
CAS
627518-40-5
Molecular Formula
C18H16FN3O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris™ JNJ 10198409 | Fischer Scientific | ₹ 27,789.89 | |
| | Tocris™ JNJ 10198409 | Fischer Scientific | ₹ 1,16,022.78 | |
 | Biotang Inc JNJ-10198409, Free Base, > 99%, 25MG, CAS#627518-40-5, M.W.325.34, PDGF Receptor Tyrosine Kinase Inhibitor IV; RWJ-540973. RS323-25MG | Biotang Inc | ₹ 80,193.68 | |
 | MilliporeSigma™ Calbiochem™ PDGFR Tyrosine Kinase Inhibitor IV | MilliporeSigma™ | ₹ 22,793.18 | |
 | Sigma Aldrich Fine Chemicals Biosciences JNJ-10198409 >=98% (HPLC), solid | 627518-40-5 | 1MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 25,888.74 | |
 | 627518-40-5 | N-(3-Fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine | A2B Chem | ₹ 2,224.56 - ₹ 11,293.92 |
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Description
- Potent platelet-derived growth factor receptor (PDGFR) inhibitor (IC50 values are 4.2 and 45 nM for PDGFRβ and PDGFRα, respectively)
- Also inhibits c-Abl, Lck, c-Src and Fyn kinases (IC50 values are 22, 100, 185 and 378 nM respectively)
- Displays antiproliferative activity in multiple tumor cell lines
- Accelerates down regulation of fibroblast genes in reprogramming of human fibroblasts into functional cardiomyocytes, within 9C cocktail.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: N-(3-Fluorophenyl)-1,4-dihydro-6,7-dimethoxyindeno[1,2-c]pyrazol-3-amine
Target: PDGF Receptor Inhibitors
Purity: 98%
CAS: 627518-40-5
Molecular Formula: C18H16FN3O2
Chemical Name or Material:
N-(3-Fluorophenyl)-1,4-dihydro-6,7-dimethoxyindeno[1,2-c]pyrazol-3-amine
Target:
PDGF Receptor Inhibitors
Purity:
98%
CAS:
627518-40-5
Molecular Formula:
C18H16FN3O2
Chemical Name or Material: N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide
Target: RIP Kinase Inhibitors
Purity: 98%
CAS: 355406-76-7
Molecular Formula: C26H21FN2O3
Chemical Name or Material:
N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide
Target:
RIP Kinase Inhibitors
Purity:
98%
CAS:
355406-76-7
Molecular Formula:
C26H21FN2O3
Chemical Name or Material: __
Target: STING Antagonists
Purity: 97%
CAS: 314054-00-7
Molecular Formula: C11H7IN2O4
Chemical Name or Material:
__
Target:
STING Antagonists
Purity:
97%
CAS:
314054-00-7
Molecular Formula:
C11H7IN2O4
Chemical Name or Material: Ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate
Target: Toll-like Receptor Antagonists
Purity: 97%
CAS: 313254-94-3
Molecular Formula: C15H14O7
Chemical Name or Material:
Ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate
Target:
Toll-like Receptor Antagonists
Purity:
97%
CAS:
313254-94-3
Molecular Formula:
C15H14O7