7222992
Tocris Bioscience™ VU 0071063
Selective activator of SUR1 Kir6.2 channels
Manufacturer: Fischer Scientific
CAS Number: 333415-38-6
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Chemical Name or Material
7-[[4-(1,1-Dimethylethyl)phenyl]methyl]-3,7-dihydro-1,3-dimethyl-1 H-purine-2,6-dione
Target
Inward Rectifier Potassium Channel Activators
Purity
0.98
CAS
333415-38-6
Molecular Formula
C18H22N4O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ VU 0071063 | Fischer Scientific | ₹ 22,288.38 | |
| | Tocris Bioscience™ VU 0071063 | Fischer Scientific | ₹ 92,918.16 | |
 | Sigma Aldrich Fine Chemicals Biosciences VU0071063 >=98% (HPLC) | 333415-38-6 | MFCD02648040 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 50,206.61 | |
 | 333415-38-6 | 7-(4-TERT-BUTYLBENZYL)-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE | A2B Chem | ₹ 2,481.24 - ₹ 25,069.08 |
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Description
- VU 0071063 is a selective activator of SUR1 Kir6.2 channels and pancreatic β-cell KATP channels (EC50 = 7 μM and 0.3-10.3 μM, respectively)
- VU 0071063 inhibits insulin secretion in pancreatic β-cells by inducing hyperpolarization of β-cell membranes and reduces voltage-dependent calcium channel activation and Ca2+ influx
- VU 0071063 is active in vivo and brain penetrant.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 7-[[4-(1,1-Dimethylethyl)phenyl]methyl]-3,7-dihydro-1,3-dimethyl-1 H-purine-2,6-dione
Target: Inward Rectifier Potassium Channel Activators
Purity: 0.98
CAS: 333415-38-6
Molecular Formula: C18H22N4O2
Chemical Name or Material:
7-[[4-(1,1-Dimethylethyl)phenyl]methyl]-3,7-dihydro-1,3-dimethyl-1 H-purine-2,6-dione
Target:
Inward Rectifier Potassium Channel Activators
Purity:
0.98
CAS:
333415-38-6
Molecular Formula:
C18H22N4O2
Chemical Name or Material: 6,7,8,9,10,11-Hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl sulfamate
Target: Hydrolase Inhibitors
Purity: 0.98
CAS: 288628-05-7
Molecular Formula: C14H15NO5S
Chemical Name or Material:
6,7,8,9,10,11-Hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl sulfamate
Target:
Hydrolase Inhibitors
Purity:
0.98
CAS:
288628-05-7
Molecular Formula:
C14H15NO5S
Chemical Name or Material: 1-[7,8-Dihydro-4-[(phenylmethyl)amino]-5 H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1 H-indole-4-carboxamide
Target: p97 ATPase Inhibitors
Purity: 0.98
CAS: 1542705-92-9
Molecular Formula: C24H23N5O2
Chemical Name or Material:
1-[7,8-Dihydro-4-[(phenylmethyl)amino]-5 H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1 H-indole-4-carboxamide
Target:
p97 ATPase Inhibitors
Purity:
0.98
CAS:
1542705-92-9
Molecular Formula:
C24H23N5O2
Chemical Name or Material: (2 E)-5-Phenyl-1-(2-thienyl)-2-penten-1-one
Target: Orphan 7-TM Receptor Antagonists
Purity: 0.98
CAS: 1239987-91-7
Molecular Formula: C15H14OS
Chemical Name or Material:
(2 E)-5-Phenyl-1-(2-thienyl)-2-penten-1-one
Target:
Orphan 7-TM Receptor Antagonists
Purity:
0.98
CAS:
1239987-91-7
Molecular Formula:
C15H14OS