7223019
Tocris Bioscience™ Ceapin A7
Selective inhibitor of ATF6α; sensitizes cells to ER stress
Manufacturer: Fischer Scientific
CAS Number: 2323027-38-7
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Chemical Name or Material
N-[1-[[2,4-bis(Trifluoromethyl)phenyl]methyl]-1 H-pyrazol-4-yl]-5-(2-furanyl)-3-isoxazolecarboxamide
Target
Other ER Stress/UPR Activators
Purity
0.98
CAS
2323027-38-7
Molecular Formula
C20H12F6N4O3
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Ceapin A7 | Fischer Scientific | ₹ 21,090.54 | |
| | Tocris Bioscience™ Ceapin A7 | Fischer Scientific | ₹ 88,041.24 | |
 | 2323027-38-7 | N-(1-(2,4-Bis(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-5-(furan-2-yl)isoxazole-3-carboxamide | A2B Chem | ₹ 3,422.40 - ₹ 25,411.32 |
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Description
- Ceapin A7 is a selective inhibitor of ATF6α (IC50=0.59 μM)
- The compound selectively inhibits ATF6α over ATF6β and other branches of the unfolded protein response (UPR)
- Ceapin A7 inhibits ER stress-induced upregulation of BiP in vitro
- Ceapin A7 inhibits cleavage and functional activation of endogenous ATF6 in response to ER stress in vitro .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N-[1-[[2,4-bis(Trifluoromethyl)phenyl]methyl]-1 H-pyrazol-4-yl]-5-(2-furanyl)-3-isoxazolecarboxamide
Target: Other ER Stress/UPR Activators
Purity: 0.98
CAS: 2323027-38-7
Molecular Formula: C20H12F6N4O3
Chemical Name or Material:
N-[1-[[2,4-bis(Trifluoromethyl)phenyl]methyl]-1 H-pyrazol-4-yl]-5-(2-furanyl)-3-isoxazolecarboxamide
Target:
Other ER Stress/UPR Activators
Purity:
0.98
CAS:
2323027-38-7
Molecular Formula:
C20H12F6N4O3
Chemical Name or Material: N-[3-[4,5-Dihydro-4-methyl-6-[[4-(4-morpholinylcarbonyl)phenyl]amino]-5-oxo-2-pyrazinyl]-2-methylphenyl]-4-(1,1-dimethylethyl)benzamide
Target: Brutons Tyrosine Kinase (BTK) Inhibitors
Purity: 0.97
CAS: 910232-84-7
Molecular Formula: C34H37N5O4
Chemical Name or Material:
N-[3-[4,5-Dihydro-4-methyl-6-[[4-(4-morpholinylcarbonyl)phenyl]amino]-5-oxo-2-pyrazinyl]-2-methylphenyl]-4-(1,1-dimethylethyl)benzamide
Target:
Brutons Tyrosine Kinase (BTK) Inhibitors
Purity:
0.97
CAS:
910232-84-7
Molecular Formula:
C34H37N5O4
Chemical Name or Material: 6 '-Fluoro-2-[4-(4-methyl-4 H-1,2,4-triazol-3-yl)-1-piperidinyl]-3,3 '-bipyridine
Target: Other Transferase Inhibitors
Purity: 0.98
CAS: 2117405-13-5
Molecular Formula: C18H19FN6
Chemical Name or Material:
6 '-Fluoro-2-[4-(4-methyl-4 H-1,2,4-triazol-3-yl)-1-piperidinyl]-3,3 '-bipyridine
Target:
Other Transferase Inhibitors
Purity:
0.98
CAS:
2117405-13-5
Molecular Formula:
C18H19FN6
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