7237165
Tocris Bioscience™ Pyr 10
Selective TRPC3 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1315323-00-2
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Chemical Name or Material
N-[4-[3,5-bis(Trifluoromethyl)-1 H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide
Target
TRPC Channel Blockers
Purity
0.98
CAS
1315323-00-2
Molecular Formula
C18H13F6N3O2S
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Pyr 10 | Fischer Scientific | ₹ 16,341.96 | |
| | Tocris Bioscience™ Pyr 10 | Fischer Scientific | ₹ 68,362.44 | |
 | Sigma Aldrich Fine Chemicals Biosciences Pyr10 >=98% (HPLC) | 1315323-00-2 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 12,682.56 | |
 | eMolecules Medchem Express / Pyr10 / 5mg / 446269836 / HY-19408 / / 1315323-00-2 / MFCD28411625 / 449.370 / C18H13F6N3O2S | eMolecules | ₹ 6,926.94 | |
 | 1315323-00-2 | Pyr10 | A2B Chem | ₹ 7,700.40 - ₹ 32,940.60 |
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Description
- Pyr 10 is a TRPC3 (transient receptor potential canonical 3) channel inhibitor (IC50 = 0.72 μM for TRPC3 mediated calcium entry in vitro ), which displays approximately 18-fold selectivity for TRPC3-mediated receptor operated calcium entry (ROCE) over STIM1/Orai1-mediated store operated calcium entry (SOCE)
- Pyr 10 inhibits NFATc3 activation and inhibits proliferation of rat ventricular cardiac fibroblasts.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N-[4-[3,5-bis(Trifluoromethyl)-1 H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide
Target: TRPC Channel Blockers
Purity: 0.98
CAS: 1315323-00-2
Molecular Formula: C18H13F6N3O2S
Chemical Name or Material:
N-[4-[3,5-bis(Trifluoromethyl)-1 H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide
Target:
TRPC Channel Blockers
Purity:
0.98
CAS:
1315323-00-2
Molecular Formula:
C18H13F6N3O2S
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