7199115
Tocris™ BC-LI-0186
Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor
Manufacturer: Fischer Scientific
CAS Number: 695207-56-8
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Chemical Name or Material
4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1 H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide
Target
Ras GTPase Inhibitors
Purity
98%
CAS
695207-56-8
Molecular Formula
C22H27N3O4S
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris™ BC-LI-0186 | Fischer Scientific | ₹ 51,000.56 | |
| | Tocris™ BC-LI-0186 | Fischer Scientific | ₹ 12,285.56 | |
 | eMolecules Medchem Express / BC-LI-0186 / 5mg / 694125030 / HY-136265 / / 695207-56-8 / [null] / 429.540 / C22H27N3O4S | eMolecules | ₹ 11,790.72 | |
 | Sigma Aldrich Fine Chemicals Biosciences BC-LI-0186 >=98% (HPLC) | 695207-56-8 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 14,391.30 | |
 | BC-LI-0186 | Aaron Chemicals LLC | ₹ 9,167.00 - ₹ 87,131.00 | |
 | BC-LI-0186 | ChemScene | ₹ 8,010.00 - ₹ 71,200.00 | |
 | 695207-56-8 | BC-LI-0186 | A2B Chem | ₹ 11,570.00 - ₹ 77,875.00 |
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Description
- Potent and high affinity leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor (IC50 = 46.1 nM; Kd = 42.1 nM for binding to LRS)
- Inhibits mTOR complex 1 activity by blocking binding to LRS without affecting catalytic activity
- Inhibits leucine-induced translocation of LRS to the lysosome.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1 H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide
Target: Ras GTPase Inhibitors
Purity: 98%
CAS: 695207-56-8
Molecular Formula: C22H27N3O4S
Chemical Name or Material:
4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1 H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide
Target:
Ras GTPase Inhibitors
Purity:
98%
CAS:
695207-56-8
Molecular Formula:
C22H27N3O4S
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