7199115

Tocris™ BC-LI-0186

Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor

Manufacturer: Fischer Scientific

CAS Number: 695207-56-8

The price for this product is unavailable. Please request a quote

Chemical Name or Material

4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1 H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide

Target

Ras GTPase Inhibitors

Purity

98%

CAS

695207-56-8

Molecular Formula

C22H27N3O4S

Other Options

Image Product Name Manufacturer Price Range
67-912-5
Tocris™ BC-LI-0186
Fischer Scientific ₹ 49,029.30
67-915
Tocris™ BC-LI-0186
Fischer Scientific ₹ 11,810.70
50-244-9004
eMolecules​ Medchem Express / BC-LI-0186 / 5mg / 694125030 / HY-136265 / / 695207-56-8 / [null] / 429.540 / C22H27N3O4S
eMolecules​ ₹ 11,334.99
50-186-8186
Sigma Aldrich Fine Chemicals Biosciences BC-LI-0186 >=98% (HPLC) | 695207-56-8 | 5MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 13,835.05
AR01LO1B
BC-LI-0186
Aaron Chemicals LLC ₹ 8,812.68 - ₹ 83,763.24
CS-0121076
BC-LI-0186
ChemScene ₹ 7,700.40 - ₹ 68,448.00
BA89443
695207-56-8 | BC-LI-0186
A2B Chem ₹ 11,122.80 - ₹ 74,865.00

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Description

  • Potent and high affinity leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor (IC50 = 46.1 nM; Kd = 42.1 nM for binding to LRS)
  • Inhibits mTOR complex 1 activity by blocking binding to LRS without affecting catalytic activity
  • Inhibits leucine-induced translocation of LRS to the lysosome.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1 H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide

Target:
Ras GTPase Inhibitors

Purity:
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CAS:
695207-56-8

Molecular Formula:
C22H27N3O4S

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