7237176
Tocris Bioscience™ NS 3728
VRAC blocker
Manufacturer: Fischer Scientific
CAS Number: 265646-85-3
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Chemical Name or Material
N-[3,5-bis(Trifluoromethyl)phenyl]-N'-[4-bromo-2-(2 H-tetrazol-5-yl)phenyl]urea
Target
Other Chloride Channel Blockers
Purity
0.98
CAS
265646-85-3
Molecular Formula
C16H9BrF6N6O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ NS 3728 | Fischer Scientific | ₹ 19,552.17 | |
| | Tocris Bioscience™ NS 3728 | Fischer Scientific | ₹ 82,178.67 | |
 | eMolecules Medchem Express / Emidurdar / 5mg / 455325932 / HY-105917 / / 265646-85-3 / [null] / 495.183 / C16H9BrF6N6O | eMolecules | ₹ 10,075.55 | |
| | Medchemexpress LLC HY-105917 5mg Medchemexpress, Endovion CAS:265646-85-3 Purity:>98% | Medchemexpress LLC | ₹ 7,187.04 | |
 | Sigma Aldrich Fine Chemicals Biosciences NS3728 >=98% (HPLC) | 265646-85-3 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 11,319.59 | |
 | Medchemexpress LLC HY-105917 10mg Medchemexpress, Endovion CAS:265646-85-3 Purity:>98% | Medchemexpress LLC | ₹ 11,678.94 | |
 | 265646-85-3 | Endovion | A2B Chem | ₹ 7,700.40 - ₹ 34,395.12 |
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Description
- NS 3728 is a volume-regulated anion channel (VRAC) blocker (IC50 = 460 nM)
- Blocks red blood cell chloride conductance (IC50 = 0.6 μM)
- NS 3728 also inhibits Ca2+-activated Cl- current (CaCC) by anoctamin (ANO) in an apparently voltage-dependent manner (IC50 against ANO1 = 2.1 and 0.7 μM at -95 and +50 mV, respectively).
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N-[3,5-bis(Trifluoromethyl)phenyl]-N'-[4-bromo-2-(2 H-tetrazol-5-yl)phenyl]urea
Target: Other Chloride Channel Blockers
Purity: 0.98
CAS: 265646-85-3
Molecular Formula: C16H9BrF6N6O
Chemical Name or Material:
N-[3,5-bis(Trifluoromethyl)phenyl]-N'-[4-bromo-2-(2 H-tetrazol-5-yl)phenyl]urea
Target:
Other Chloride Channel Blockers
Purity:
0.98
CAS:
265646-85-3
Molecular Formula:
C16H9BrF6N6O
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