69-735-0

Tocris Bioscience™ NS 3728

Manufacturer: Fischer Scientific

CAS Number: 265646-85-3

Select a Size

Pack Size SKU Availability Price
Each of 1 69-735-0-Each-of-1 In Stock ₹ 85,482.72

69-735-0 - Each of 1

₹ 85,482.72

In Stock

Quantity

1

Base Price: ₹ 85,482.72

GST (18%): ₹ 15,386.89

Total Price: ₹ 1,00,869.61

Chemical Name or Material

N-[3,5-bis(Trifluoromethyl)phenyl]-N'-[4-bromo-2-(2 H-tetrazol-5-yl)phenyl]urea

Quantity

50 mg

Molecular Formula

C16H9BrF6N6O

CAS

265646-85-3

Target

Other Chloride Channel Blockers

Purity

0.98

Other Options

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Selective USP25 and USP28 inhibitor...

Description

  • NS 3728 is a volume-regulated anion channel (VRAC) blocker (IC50 = 460 nM)
  • Blocks red blood cell chloride conductance (IC50 = 0.6 μM)
  • NS 3728 also inhibits Ca2+-activated Cl- current (CaCC) by anoctamin (ANO) in an apparently voltage-dependent manner (IC50 against ANO1 = 2.1 and 0.7 μM at -95 and +50 mV, respectively).

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C