7223005
Tocris Bioscience™ NCT 02
Molecular glue; induces degradation of CCNK and CDK12
Manufacturer: Fischer Scientific
CAS Number: 790245-61-3
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Chemical Name or Material
6,7-Dihydro-N-(5-methyl-2-thiazolyl)-5 H-indeno[5,6-b]furan-3-acetamide
Target
Molecular Glues
Purity
0.98
CAS
790245-61-3
Molecular Formula
C17H16N2O2S
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ NCT 02 | Fischer Scientific | ₹ 27,011.50 | |
| | Tocris Bioscience™ NCT 02 | Fischer Scientific | ₹ 1,13,030.00 | |
 | Medchemexpress LLC HY-W181530 10mg , NCT02 CAS:790245-61-3 Purity:>98% | Medchemexpress LLC | ₹ 17,755.50 | |
 | eMolecules Medchem Express / NCT02 / 10mg / 716993978 / HY-W181530 / / 790245-61-3 / [null] / 312.390 / C17H16N2O2S | eMolecules | ₹ 24,891.52 | |
 | NCT02 | ChemScene | ₹ 22,428.00 - ₹ 64,792.00 |
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Description
- NCT 02 acts as a molecular glue that induces proteasomal degradation of CCNK and CDK12 in colorectal cancer spheroid cells in vitro (IC50 ≤ 50 μM)
- NCT 02 also induces apoptosis and the downregulation of genes involved in DNA damage repair.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 6,7-Dihydro-N-(5-methyl-2-thiazolyl)-5 H-indeno[5,6-b]furan-3-acetamide
Target: Molecular Glues
Purity: 0.98
CAS: 790245-61-3
Molecular Formula: C17H16N2O2S
Chemical Name or Material:
6,7-Dihydro-N-(5-methyl-2-thiazolyl)-5 H-indeno[5,6-b]furan-3-acetamide
Target:
Molecular Glues
Purity:
0.98
CAS:
790245-61-3
Molecular Formula:
C17H16N2O2S
Chemical Name or Material: 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2 H)-phthalazinone
Target: Poly(ADP-ribose) Polymerase Inhibitors
Purity: 0.98
CAS: 763113-22-0
Molecular Formula: C24H23FN4O3
Chemical Name or Material:
4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2 H)-phthalazinone
Target:
Poly(ADP-ribose) Polymerase Inhibitors
Purity:
0.98
CAS:
763113-22-0
Molecular Formula:
C24H23FN4O3
Chemical Name or Material: (1 R,3 R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1 H-pyrido[3,4-b]indole-3-carboxylate
Target: Glutathione Peroxidase 4/GPX4
Purity: 0.98
CAS: 1219810-15-7
Molecular Formula: C23H21ClN2O5
Chemical Name or Material:
(1 R,3 R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1 H-pyrido[3,4-b]indole-3-carboxylate
Target:
Glutathione Peroxidase 4/GPX4
Purity:
0.98
CAS:
1219810-15-7
Molecular Formula:
C23H21ClN2O5
Chemical Name or Material: N-[1-[[2,4-bis(Trifluoromethyl)phenyl]methyl]-1 H-pyrazol-4-yl]-5-(2-furanyl)-3-isoxazolecarboxamide
Target: Other ER Stress/UPR Activators
Purity: 0.98
CAS: 2323027-38-7
Molecular Formula: C20H12F6N4O3
Chemical Name or Material:
N-[1-[[2,4-bis(Trifluoromethyl)phenyl]methyl]-1 H-pyrazol-4-yl]-5-(2-furanyl)-3-isoxazolecarboxamide
Target:
Other ER Stress/UPR Activators
Purity:
0.98
CAS:
2323027-38-7
Molecular Formula:
C20H12F6N4O3