7250172
Tocris Bioscience™ dCeMM2
Molecular glue Degrader; induces ubiquitination and degradation of cyclin K
Manufacturer: Fischer Scientific
CAS Number: 296771-07-8
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Chemical Name or Material
N-(5-Chloro-2-pyridinyl)-2-(5 H-1,2,4-triazino[5,6-b]indol-3-ylthio)acetamide
Target
Molecular Glues
Purity
0.98
CAS
296771-07-8
Molecular Formula
C16H11ClN6OS
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ dCeMM2 | Fischer Scientific | ₹ 15,435.02 | |
| | Tocris Bioscience™ dCeMM2 | Fischer Scientific | ₹ 64,768.92 | |
 | 296771-07-8 | N-(5-Chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide | A2B Chem | ₹ 10,951.68 - ₹ 62,801.04 |
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Description
- dCeMM2 is a molecular glue degrader
- Induces ubiquitination and degradation of cyclin K by eliciting an interaction of CDK12-cyclin K with a CRL4B ligase complex
- dCeMM2 displays near-total degradation of protein at 2.5 μM within 2h
- Cell-permeable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N-(5-Chloro-2-pyridinyl)-2-(5 H-1,2,4-triazino[5,6-b]indol-3-ylthio)acetamide
Target: Molecular Glues
Purity: 0.98
CAS: 296771-07-8
Molecular Formula: C16H11ClN6OS
Chemical Name or Material:
N-(5-Chloro-2-pyridinyl)-2-(5 H-1,2,4-triazino[5,6-b]indol-3-ylthio)acetamide
Target:
Molecular Glues
Purity:
0.98
CAS:
296771-07-8
Molecular Formula:
C16H11ClN6OS
Chemical Name or Material: 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
Target: Hedgehog Signaling Inhibitors
Purity: 0.98
CAS: 879085-55-9
Molecular Formula: C19H14Cl2N2O3S
Chemical Name or Material:
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
Target:
Hedgehog Signaling Inhibitors
Purity:
0.98
CAS:
879085-55-9
Molecular Formula:
C19H14Cl2N2O3S
Chemical Name or Material: 1-[[N-tert-Butoxycarbonyl-L-tert-leucyl-trans-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-L-prolyl]amino]-N-(cyclopropylsulfonyl)-(1 R,2 S)-2-vinylcyclopropane-1-carboxamide
Target: CRISPR Reagents
Purity: 0.98
CAS: 630420-16-5
Molecular Formula: C35H46ClN5O9S
Chemical Name or Material:
1-[[N-tert-Butoxycarbonyl-L-tert-leucyl-trans-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-L-prolyl]amino]-N-(cyclopropylsulfonyl)-(1 R,2 S)-2-vinylcyclopropane-1-carboxamide
Target:
CRISPR Reagents
Purity:
0.98
CAS:
630420-16-5
Molecular Formula:
C35H46ClN5O9S
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