7161692

Tocris Bioscience™ VAS 2870

NADPH oxidase (Nox) inhibitor

Manufacturer: Fischer Scientific

CAS Number: 722456-31-7

The price for this product is unavailable. Please request a quote

Chemical Name or Material

7-(2-Benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine

Molecular Formula

C18H12N6OS

Purity

98%

CAS

722456-31-7

Formula Weight

360.39

Other Options

Image Product Name Manufacturer Price Range
66-542-5RD
Tocris Bioscience™ VAS 2870
Fischer Scientific ₹ 32,983.38
66-545
Tocris Bioscience™ VAS 2870
Fischer Scientific ₹ 8,521.78
49-200-010MG
MilliporeSigma™ Calbiochem™ NOX Inhibitor III, VAS2870
MilliporeSigma™ ₹ 15,144.12
50-243-9817
eMolecules​ Ambeed / 2-((3-Benzyl-3H-[123]triazolo[45-d]pyrimidin-7-yl)thio)benzo[d]oxazole / 5mg / 525225251 / A564124 / / 722456-31-7 / MFCD03407188 / 360.400 / C18H12N6OS
eMolecules​ ₹ 4,255.75
AR00FINI
1,3-benzoxazol-2-yl 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide
Aaron Chemicals LLC ₹ 5,903.64 - ₹ 64,854.48
AH22914
722456-31-7 | 1,3-benzoxazol-2-yl 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide
A2B Chem ₹ 2,481.24 - ₹ 7,272.60

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Description

  • Inhibits PMA-stimulated oxidative burst in HL-60 cells (IC50 = 2 μM) Inhibits oxidized-LDL-mediated, but not basal, ROS production in HUVECs in vitro Also inhibits PDGF-mediated Nox activation and ROS formation in vascular smooth muscle cells (VSMCs) and abolishes PDGF-dependent migration of VSMCs, while having no effect on proliferation Enhances TGF-β-induced apoptosis of liver tumor cells

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C

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NADPH oxidase (Nox) inhibitor...


Chemical Name or Material:
7-(2-Benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine

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C18H12N6OS

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98%

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722456-31-7

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