77-625-0

Tocris Bioscience™ EED 226

Manufacturer: Fischer Scientific

CAS Number: 2083627-02-3

Select a Size

Pack Size SKU Availability Price
Each of 1 77-625-0-Each-of-1 In Stock ₹ 67,763.52

77-625-0 - Each of 1

₹ 67,763.52

In Stock

Quantity

1

Base Price: ₹ 67,763.52

GST (18%): ₹ 12,197.434

Total Price: ₹ 79,960.954

Chemical Name or Material

N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine

Quantity

50 mg

Molecular Formula

C17H15N5O3S

CAS

2083627-02-3

Target

EED

Other Options

Image Product Name Manufacturer Price Range
7249494
Tocris Bioscience™ EED 226
Fischer Scientific --
77-621-0
Tocris Bioscience™ EED 226
Fischer Scientific ₹ 16,145.17
50-226-0390
Medchemexpress LLC HY-101117 25mg , EED226 CAS:2083627-02-3 Purity:>98%
Medchemexpress LLC ₹ 14,823.27
AC468141000
Thermo Scientific™ EED226, 95%
Thermo Scientific™ ₹ 52,277.16
50-202-8647
Medchemexpress LLC HY-101117 10mg Medchemexpress, EED226 CAS:2083627-02-3 Purity:>98%
Medchemexpress LLC ₹ 8,893.96

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Description

  • EED 226 is a potent (IC50 = 23.4 nM) and selective EED inhibitor
  • It inhibits PRC2 activity by binding to the H3K27me3 pocket of EED
  • The compound shows selectivity for PRC2 complex over protein methyltransferases, kinases, and other protein classes
  • In vitro , EED 226 regulates histone H3K27 methylation and PRC2 target gene expression
  • In vivo , it induces tumor regression in a mouse xenograft model
  • EED 226 is orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Compare Similar Items

Show Difference

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Fischer Scientific

77-625-0

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Chemical Name or Material:
N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine

Quantity:
50 mg

Molecular Formula:
C17H15N5O3S

CAS:
2083627-02-3

Target:
EED

Img

Tocris Bioscience™

77-685

--


Chemical Name or Material:
N-(24-Azido-12,20-dioxo-3,6,9-trioxa-16,17-dithia-13,21-diazatetracosyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

Quantity:
5 mg

Molecular Formula:
C27H48N8O7S3

CAS:
2866429-93-6

Target:
General Laboratory Research Reagent

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SPEX CertiPrep

77-7

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Chemical Name or Material:
Turbidity QC Sample

Quantity:
15 mL

Molecular Formula:
__

CAS:
__

Target:
__

Img

Fischer Scientific

77-711-0

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Chemical Name or Material:
N-[(1-Methyl-1 H-imidazol-4-yl)methyl]-4-(4-methyl-1-piperidinyl)-2-pyrimidinamine

Quantity:
10 mg

Molecular Formula:
C15H22N6

CAS:
2757254-99-0

Target:
Hydrolase Inhibitors