7235739
Tocris™ Takinib
Potent and selective TAK1/MAP3K7 kinase inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1111556-37-6
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Chemical Name or Material
N1-(1-Propyl-1 H-benzimidazol-2-yl)-1,3-benzenedicarboxamide
Target
Other Kinase Inhibitors
Purity
0.98
CAS
1111556-37-6
Molecular Formula
C18H18N4O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris™ Takinib | Fischer Scientific | ₹ 41,207.00 | |
| | Tocris™ Takinib | Fischer Scientific | ₹ 10,012.50 | |
 | 1111556-37-6 | Takinib | A2B Chem | ₹ 2,581.00 - ₹ 91,047.00 |
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Description
- Takinib is a potent and selective TAK1/MAP3K7 kinase inhibitor (IC50 = 8.2-9.5 nM)
- Selective for TAK1 over IRAK4, IRAK1, GCK, CLK2 and MINK1 (IC50 values = 120, 390, 430, 430 and 1900 nM, respectively)
- Demonstrates weak inhibition at Src and Yes1
- Exhibits no inhibition of MAP2K or other MAP3K family members
- Induces apoptosis following TNF-α stimulation in in vitro models of rheumatoid arthritis and metastatic breast cancer.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: N1-(1-Propyl-1 H-benzimidazol-2-yl)-1,3-benzenedicarboxamide
Target: Other Kinase Inhibitors
Purity: 0.98
CAS: 1111556-37-6
Molecular Formula: C18H18N4O2
Chemical Name or Material:
N1-(1-Propyl-1 H-benzimidazol-2-yl)-1,3-benzenedicarboxamide
Target:
Other Kinase Inhibitors
Purity:
0.98
CAS:
1111556-37-6
Molecular Formula:
C18H18N4O2
Chemical Name or Material: N-[(5-Methyl-3-isoxazolyl)carbonyl]-L-alanyl-L-valyl-N-[(1 S,2 E)-4-oxo-1-[[(3 S)-2-oxo-3-pyrrolidinyl]methyl]-4-(phenylmethoxy)-2-buten-1-yl]-L-leucinamide
Target: Additional Synthetic Protease Inhibitors
Purity: 0.98
CAS: 884650-98-0
Molecular Formula: C35H48N6O8
Chemical Name or Material:
N-[(5-Methyl-3-isoxazolyl)carbonyl]-L-alanyl-L-valyl-N-[(1 S,2 E)-4-oxo-1-[[(3 S)-2-oxo-3-pyrrolidinyl]methyl]-4-(phenylmethoxy)-2-buten-1-yl]-L-leucinamide
Target:
Additional Synthetic Protease Inhibitors
Purity:
0.98
CAS:
884650-98-0
Molecular Formula:
C35H48N6O8
Chemical Name or Material: N'-(4-Fluoro-5-methyl-[1,1 '-biphenyl]-3-carbonyl)-3-hydroxybenzenesulfonohydrazide
Target: Histone Acetyltransferase Inhibitors
Purity: 0.98
CAS: 2229025-70-9
Molecular Formula: C20H17FN2O4S
Chemical Name or Material:
N'-(4-Fluoro-5-methyl-[1,1 '-biphenyl]-3-carbonyl)-3-hydroxybenzenesulfonohydrazide
Target:
Histone Acetyltransferase Inhibitors
Purity:
0.98
CAS:
2229025-70-9
Molecular Formula:
C20H17FN2O4S
Chemical Name or Material: 4-(4-Chlorophenyl)-4-[4-(1 H-pyrazol-4-yl)phenyl]piperidine hydrochloride
Target: Akt (Protein Kinase B) Inhibitors
Purity: 0.98
CAS: __
Molecular Formula: C20H20ClN3.HCl
Chemical Name or Material:
4-(4-Chlorophenyl)-4-[4-(1 H-pyrazol-4-yl)phenyl]piperidine hydrochloride
Target:
Akt (Protein Kinase B) Inhibitors
Purity:
0.98
CAS:
__
Molecular Formula:
C20H20ClN3.HCl