7249488

Tocris Bioscience™ BAY 1797

Selective P2X4 antagonist

Manufacturer: Fischer Scientific

CAS Number: 2055602-83-8

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Chemical Name or Material

N-[3-(Aminosulfonyl)-4-(3-chlorophenoxy)phenyl]benzeneacetamide

CAS

2055602-83-8

Target

P2X4

Molecular Formula

C20H17ClN2O4S

Other Options

Image Product Name Manufacturer Price Range
75-731-0
Tocris Bioscience™ BAY 1797
Fischer Scientific ₹ 18,566.52
75-735-0
Tocris Bioscience™ BAY 1797
Fischer Scientific --

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Description

  • BAY 1797 is a selective purinergic P2X4 receptor antagonist (IC50 values are 108, 112 and 233 nM for the human, mouse and rat P2X4, respectively)
  • It is selective for P2X4 over P2X3, P2X7, and P2X1 receptors (IC50 values are 8.3, 10.6 and >50 μM, respectively, for the human receptors)
  • BAY 1797 dose-dependently reduces prostaglandin E2 levels and exhibits anti-inflammatory and analgesic effects in an in vivo model of inflammatory pain
  • Orally active.

SAFETY INFORMATION

  • Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Selective P2X4 antagonist...


Chemical Name or Material:
N-[3-(Aminosulfonyl)-4-(3-chlorophenoxy)phenyl]benzeneacetamide

CAS:
2055602-83-8

Target:
P2X4

Molecular Formula:
C20H17ClN2O4S

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Target:
Antiviral Compounds

Molecular Formula:
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