7224941
Tocris Bioscience™ CBR-470-1
PGK1 inhibitior; activates Nrf2
Manufacturer: Fischer Scientific
CAS Number: 2416095-06-0
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Chemical Name or Material
(3 R,4 S)-rel-4-[(4-Chlorophenyl)sulfonyl]tetrahydro-N-(2-methylpropyl)-3-thiophenamine-1,1-dioxide
Target
Nrf2 Activators
Purity
98%
CAS
2416095-06-0
Molecular Formula
C14H20ClNO4S2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ CBR-470-1 | Fischer Scientific | ₹ 22,887.30 | |
| | Tocris Bioscience™ CBR-470-1 | Fischer Scientific | ₹ 95,998.32 | |
 | Medchemexpress LLC HY-134205A 5mg Medchemexpress, CBR-470-1 CAS:2416095-06-0 Purity:>98% | Medchemexpress LLC | ₹ 6,288.66 | |
 | 2416095-06-0 | CBR-470-1 | A2B Chem | ₹ 9,326.04 - ₹ 61,432.08 |
Related Products
Description
- CBR-470-1 is a phosphoglycerate kinase 1 (PGK1) inhibitor
- CBR-470-1 promotes accumulation of the reactive metabolites methylglyoxal (MGO) resulting in KEAP1 modification and dimerization, which in turn leads to activation of the Nrf2 transcriptional program
- CBR-470-1 protects SH-SY5Y neuroblastoma cells from MPP+-induced cytotoxicity via the Keap1-Nrf2 cascade.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: (3 R,4 S)-rel-4-[(4-Chlorophenyl)sulfonyl]tetrahydro-N-(2-methylpropyl)-3-thiophenamine-1,1-dioxide
Target: Nrf2 Activators
Purity: 98%
CAS: 2416095-06-0
Molecular Formula: C14H20ClNO4S2
Chemical Name or Material:
(3 R,4 S)-rel-4-[(4-Chlorophenyl)sulfonyl]tetrahydro-N-(2-methylpropyl)-3-thiophenamine-1,1-dioxide
Target:
Nrf2 Activators
Purity:
98%
CAS:
2416095-06-0
Molecular Formula:
C14H20ClNO4S2
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