73-921-0
Tocris Bioscience™ 5-Ph-IAA
Manufacturer: Fischer Scientific
CAS Number: 168649-23-8
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 73-921-0-Each-of-1 | In Stock | ₹ 15,392.24 |
73-921-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,392.24
GST (18%): ₹ 2,770.603
Total Price: ₹ 18,162.843
Chemical Name or Material
5-Phenyl-1 H-indole-3-acetic acid
Quantity
10 mg
Molecular Formula
C16H13NO2
CAS
168649-23-8
Target
Active Degraders
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ 5-Ph-IAA | Fischer Scientific | -- | |
| | Tocris Bioscience™ 5-Ph-IAA | Fischer Scientific | ₹ 64,041.66 | |
 | Medchemexpress LLC HY-134653 10mg , 5-Ph-IAA CAS:168649-23-8 Purity:>98% | Medchemexpress LLC | ₹ 10,780.56 | |
| | Medchemexpress LLC HY-134653 25mg , 5-Ph-IAA CAS:168649-23-8 Purity:>98% | Medchemexpress LLC | ₹ 21,561.12 | |
 | Medchemexpress LLC 5-Ph-IAA | 168649-23-8 | MFCD21897325 | 5 mg | Medchemexpress LLC | ₹ 6,288.66 | |
 | eMolecules Medchem Express / 5-Ph-IAA / 5mg / 587658681 / HY-134653 / / 168649-23-8 / [null] / 251.285 / C16H13NO2 | eMolecules | ₹ 8,816.10 | |
 | 168649-23-8 | 1H-Indole-3-acetic acid, 5-phenyl- | A2B Chem | ₹ 5,219.16 - ₹ 16,256.40 |
Related Products
Description
- 5-Ph-IAA is a selective and potent "Bump & Hole" TAG Degrader (DC50,6h = 17.0 nM, T1/2 = 62.3 min), for use within an auxin-inducible degron (AID2) system
- 5-Ph-IAA is an analog (the “Bump”) of natural auxin that induces rapid degradation of a target protein tagged with a single-point mutant OsTIR1F74G F-box protein (the "Hole" or mini AID)
- The induced degradation is reversible 3 h after washout with fresh medium
- 5-Ph-IAA shows rapid depletion of mAID-tagged nuclear and cytoplasmic proteins in proliferating and non-proliferating mammalian cells with no detectable basal degradation, lower cytotoxicity level, increased potency and faster degradation of the reporter in comparison with the conventional AID system
- The AID2 system also works in budding yeast and fission yeast, and it can control protein expression in multiple mouse organs in vivo
- To enquire about custom knock-in cell lines for the AID2 platform, please email TPD@bio-techne.com Plasmid vectors for the AAV transfection and CRISPR-mediated knock-in of OsTIR1F74G and mAID tag are available from Addgene .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 5-Phenyl-1 H-indole-3-acetic acid
Quantity: 10 mg
Molecular Formula: C16H13NO2
CAS: 168649-23-8
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
5-Phenyl-1 H-indole-3-acetic acid
Quantity:
10 mg
Molecular Formula:
C16H13NO2
CAS:
168649-23-8
Target:
Active Degraders
Purity:
0.98
Chemical Name or Material: 5-Phenyl-1 H-indole-3-acetic acid
Quantity: 50 mg
Molecular Formula: C16H13NO2
CAS: 168649-23-8
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
5-Phenyl-1 H-indole-3-acetic acid
Quantity:
50 mg
Molecular Formula:
C16H13NO2
CAS:
168649-23-8
Target:
Active Degraders
Purity:
0.98
Chemical Name or Material: 3-(4-(3-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)piperazin-1-yl)-N-(8-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)octyl)propanamide
Quantity: 5 mg
Molecular Formula: C47H56ClFN8O8
CAS: __
Target: Active Degrader Negative Controls
Purity: 0.98
Chemical Name or Material:
3-(4-(3-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)piperazin-1-yl)-N-(8-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)octyl)propanamide
Quantity:
5 mg
Molecular Formula:
C47H56ClFN8O8
CAS:
__
Target:
Active Degrader Negative Controls
Purity:
0.98
Chemical Name or Material: (2 S,4 R)-1-(-2-(11-(4-(3-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)piperazin-1-yl)-11-oxoundecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Quantity: 5 mg
Molecular Formula: C55H71ClFN9O7S
CAS: __
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
(2 S,4 R)-1-(-2-(11-(4-(3-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)piperazin-1-yl)-11-oxoundecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Quantity:
5 mg
Molecular Formula:
C55H71ClFN9O7S
CAS:
__
Target:
Active Degraders
Purity:
0.98