74-241-0
Tocris Bioscience™ EMI 48
Manufacturer: Tocris Bioscience™
CAS Number: 34564-13-1
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 74-241-0-Each-of-1 | In Stock | ₹ 22,331.16 |
74-241-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,331.16
GST (18%): ₹ 4,019.609
Total Price: ₹ 26,350.769
Chemical Name or Material
7-(Diethylamino)-3-(5-methyl-2-benzoxazolyl)-2 H-1-benzopyran-2-one
Quantity
10 mg
Molecular Formula
C21H20N2O3
CAS
34564-13-1
Target
EGF Receptor Inhibitors
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 34564-13-1 | 7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone | A2B Chem | ₹ 26,352.48 - ₹ 1,51,270.08 |
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Description
- EMI 48 is an inhibitor of mutant EGFR; it inhibits L858R/T970M/C797S mutants and ex19del/T790M/C797S triple mutants (inhibitory effects at 5 μM) but has no effect on wild-type EGFR
- EMI 48 induces EGFR degradation (<5 μM), and inhibits activation of ERK, S6 and AKT.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: 7-(Diethylamino)-3-(5-methyl-2-benzoxazolyl)-2 H-1-benzopyran-2-one
Quantity: 10 mg
Molecular Formula: C21H20N2O3
CAS: 34564-13-1
Target: EGF Receptor Inhibitors
Purity: 0.98
Chemical Name or Material:
7-(Diethylamino)-3-(5-methyl-2-benzoxazolyl)-2 H-1-benzopyran-2-one
Quantity:
10 mg
Molecular Formula:
C21H20N2O3
CAS:
34564-13-1
Target:
EGF Receptor Inhibitors
Purity:
0.98
Chemical Name or Material: 2-(2,6-Dioxo-3-piperidinyl)-4-[[2-[3-[4-[6-[6-[(2 R)-2-(3-fluorophenyl)-1-pyrrolidinyl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-1-piperazinyl]-3-oxopropoxy]ethyl]amino]-1 H-isoindole-1,3(2 H)-dione
Quantity: 5 mg
Molecular Formula: C43H43FN10O6
CAS: 2412055-93-5
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
2-(2,6-Dioxo-3-piperidinyl)-4-[[2-[3-[4-[6-[6-[(2 R)-2-(3-fluorophenyl)-1-pyrrolidinyl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-1-piperazinyl]-3-oxopropoxy]ethyl]amino]-1 H-isoindole-1,3(2 H)-dione
Quantity:
5 mg
Molecular Formula:
C43H43FN10O6
CAS:
2412055-93-5
Target:
Active Degraders
Purity:
0.98
Chemical Name or Material: 2-(1-Methyl-2,6-dioxo-3-piperidinyl)-4-[[2-[3-[4-[6-[6-[(2 R)-2-(3-fluorophenyl)-1-pyrrolidinyl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-1-piperazinyl]-3-oxopropoxy]ethyl]amino]-1 H-isoindole-1,3(2 H)-dione
Quantity: 5 mg
Molecular Formula: C44H45FN10O6
CAS: __
Target: Active Degrader Negative Controls
Purity: 0.98
Chemical Name or Material:
2-(1-Methyl-2,6-dioxo-3-piperidinyl)-4-[[2-[3-[4-[6-[6-[(2 R)-2-(3-fluorophenyl)-1-pyrrolidinyl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-1-piperazinyl]-3-oxopropoxy]ethyl]amino]-1 H-isoindole-1,3(2 H)-dione
Quantity:
5 mg
Molecular Formula:
C44H45FN10O6
CAS:
__
Target:
Active Degrader Negative Controls
Purity:
0.98
Chemical Name or Material: N-[[4-[3-[2,6-Difluoro-3-[(propylsulfonyl)amino]benzoyl]-1 H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]methyl]-5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1 H-isoindol-5-yl]amino]pentanamide
Quantity: 5 mg
Molecular Formula: C42H39F2N7O8S
CAS: 2417296-82-1
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
N-[[4-[3-[2,6-Difluoro-3-[(propylsulfonyl)amino]benzoyl]-1 H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]methyl]-5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1 H-isoindol-5-yl]amino]pentanamide
Quantity:
5 mg
Molecular Formula:
C42H39F2N7O8S
CAS:
2417296-82-1
Target:
Active Degraders
Purity:
0.98