78-231-0

Tocris Bioscience™ AZD 4547

Manufacturer: Fischer Scientific

CAS Number: 1035270-39-3

Select a Size

Pack Size SKU Availability Price
Each of 1 78-231-0-Each-of-1 In Stock ₹ 22,373.94

78-231-0 - Each of 1

₹ 22,373.94

In Stock

Quantity

1

Base Price: ₹ 22,373.94

GST (18%): ₹ 4,027.309

Total Price: ₹ 26,401.249

Chemical Name or Material

rel-N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]benzamide

Quantity

10 mg

Molecular Formula

C26H33N5O3

CAS

1035270-39-3

Target

FGF Receptor Inhibitors

Other Options

Image Product Name Manufacturer Price Range
7249496
Tocris Bioscience™ AZD 4547
Fischer Scientific --
78-235-0
Tocris Bioscience™ AZD 4547
Fischer Scientific --
50-226-0058
Medchemexpress LLC HY-13330 50mg , AZD4547 CAS:1035270-39-3 Purity:>98%
Medchemexpress LLC ₹ 16,620.03
50-151-433
Biotang Inc AZD4547, Free Base, > 99%, 50MG, M.W. 463.57, C26H33N5O3, CAS#1035270-39-3.
Biotang Inc ₹ 24,974.96
NC0660421
Selleck Chemical LLC AZD4547 10mg 1035270-39-3
Selleck Chemical LLC ₹ 20,226.38
50-242-5826
eMolecules​ Ambeed / rel-N-(5-(35-Dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3R5S)-35-dimethylpiperazin-1-yl)benzamide / 1mg / 713090386 / A868383 / / 1035270-39-3 / MFCD22580423 / 463.582 / C26H33N5O3
eMolecules​ ₹ 2,065.42
50-202-8986
Medchemexpress LLC HY-13330 10mg Medchemexpress, AZD4547 CAS:1035270-39-3 Purity:>98%
Medchemexpress LLC ₹ 8,265.10

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Description

  • AZD 4547 is a potent and selective FGFR1, FGFR3 and FGFR2 tyrosine kinase inhibitor (IC50 values are 0.2 1.8, and 2.5 nM, respectively)
  • It shows selectivity for FGFR across a range of unrelated tyrosine and serine/threonine kinases, including IGFR (>2,900-fold), CDK2 (>50,000-fold), and p38 (>50,000-fold)
  • In vitro , it has antiproliferative effects on tumor cell lines with deregulated FGFR expression
  • In vivo , AZD 4547 exhibits dose-dependent inhibition of tumor growth in an FGFR-driven human tumor xenograft mice model
  • It suppresses osteoclastogenesis and tumor-induced osteolysis in an orthotopic breast cancer bone metastasis mouse model
  • AZD 4547 is orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Compare Similar Items

Show Difference

Img

Fischer Scientific

78-231-0

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Chemical Name or Material:
rel-N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]benzamide

Quantity:
10 mg

Molecular Formula:
C26H33N5O3

CAS:
1035270-39-3

Target:
FGF Receptor Inhibitors

Img

Fischer Scientific

78-235-0

--


Chemical Name or Material:
rel-N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]benzamide

Quantity:
50 mg

Molecular Formula:
C26H33N5O3

CAS:
1035270-39-3

Target:
FGF Receptor Inhibitors

Img

Fischer Scientific

78-251-0

--


Chemical Name or Material:
7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one

Quantity:
10 mg

Molecular Formula:
C18H20N8O2

CAS:
2230820-11-6

Target:
DNA-dependent Protein Kinase Inhibitors

Img

Fischer Scientific

78-255-0

--


Chemical Name or Material:
7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one

Quantity:
50 mg

Molecular Formula:
C18H20N8O2

CAS:
2230820-11-6

Target:
DNA-dependent Protein Kinase Inhibitors