74-891-0
Tocris Bioscience™ TCH-165
Manufacturer: Fischer Scientific
CAS Number: 1446350-60-2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 74-891-0-Each-of-1 | In Stock | ₹ 23,807.50 |
74-891-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,807.50
GST (18%): ₹ 4,285.35
Total Price: ₹ 28,092.85
Chemical Name or Material
Ethyl (4 R,5 R)-rel-1-benzyl-5-(4-(benzylamino)phenyl)-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1 H-imidazole-4-carboxylate
Quantity
10 mg
Molecular Formula
C39H37N3O3
CAS
1446350-60-2
Target
Proteasome Modulators
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ TCH-165 | Fischer Scientific | -- | |
| | Tocris Bioscience™ TCH-165 | Fischer Scientific | ₹ 99,858.00 |
Related Products
Description
- TCH-165 is an enhancer of 20S proteasome assembly
- TCH-165 regulates the dynamic equilibrium between the 20S and 26S proteasome complexes, favoring 20S-mediated protein degradation
- TCH-165 enhances the proteolytic activity of the 20S proteasome by increasing substrate accessibility to the 20S catalytic chamber through 20S gate opening
- TCH-165 enhances 20S-mediated degradation of IDPs, α-syn, and tau in vitro , and does not induce the degradation of structured proteins such as GAPDH
- TCH-165 enhances c-MYC degradation by the 20S proteasome, which reduces c-MYC levels in vivo , and is effective in bortezomib (Cat
- No
- 7282) resistant cells
- TCH-165 down-regulates c-MYC target genes and inhibits cancer cell proliferation and tumor growth in vivo .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: Ethyl (4 R,5 R)-rel-1-benzyl-5-(4-(benzylamino)phenyl)-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1 H-imidazole-4-carboxylate
Quantity: 10 mg
Molecular Formula: C39H37N3O3
CAS: 1446350-60-2
Target: Proteasome Modulators
Purity: 0.98
Chemical Name or Material:
Ethyl (4 R,5 R)-rel-1-benzyl-5-(4-(benzylamino)phenyl)-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1 H-imidazole-4-carboxylate
Quantity:
10 mg
Molecular Formula:
C39H37N3O3
CAS:
1446350-60-2
Target:
Proteasome Modulators
Purity:
0.98
Chemical Name or Material: Ethyl (4 R,5 R)-rel-1-benzyl-5-(4-(benzylamino)phenyl)-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1 H-imidazole-4-carboxylate
Quantity: 50 mg
Molecular Formula: C39H37N3O3
CAS: 1446350-60-2
Target: Proteasome Modulators
Purity: 0.98
Chemical Name or Material:
Ethyl (4 R,5 R)-rel-1-benzyl-5-(4-(benzylamino)phenyl)-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1 H-imidazole-4-carboxylate
Quantity:
50 mg
Molecular Formula:
C39H37N3O3
CAS:
1446350-60-2
Target:
Proteasome Modulators
Purity:
0.98
Chemical Name or Material: __
Quantity: 1 Kit
Molecular Formula: __
CAS: __
Target: __
Purity: __
Chemical Name or Material:
__
Quantity:
1 Kit
Molecular Formula:
__
CAS:
__
Target:
__
Purity:
__
Chemical Name or Material: N-[[(1 R,2 R)-2-(2,3-Dihydro-4-benzofuranyl)cyclopropyl]methyl]propanamide
Quantity: 10 mg
Molecular Formula: C15H19NO2
CAS: 609799-22-6
Target: Melatonin (MT) Receptor Agonists
Purity: 0.98
Chemical Name or Material:
N-[[(1 R,2 R)-2-(2,3-Dihydro-4-benzofuranyl)cyclopropyl]methyl]propanamide
Quantity:
10 mg
Molecular Formula:
C15H19NO2
CAS:
609799-22-6
Target:
Melatonin (MT) Receptor Agonists
Purity:
0.98