75-775-0

Tocris Bioscience™ 3-Mercaptopicolinic acid hydrochloride

Manufacturer: Tocris Bioscience™

CAS Number: 320386-54-7

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Chemical Name or Material

3-Mercapto-2-pyridinecarboxylic acid hydrochloride

Quantity

50 mg

Molecular Formula

C6H5NO2S.HCl

CAS

320386-54-7

Target

PCK1

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Description

  • 3-Mercaptopicolinic acid hydrochloride is a phospoenolpyruvate carboxykinase (PEPCK) inhibitor (IC50 = 7.5 μM at hPEPCK)
  • Inhibits glucose synthesis
  • In vitro , 3-Mercaptopicolinic acid reduces proliferation of Treg cells, induces myogenic differentiation of C2C12 cells, and reduces colony growth formation of MCF7 cells
  • Also sensitizes melanoma cells to Vemurafenib (Cat
  • No
  • 7309) via inhibition of cytoplasmic PEPCK.

SAFETY INFORMATION

  • Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Chemical Name or Material:
3-Mercapto-2-pyridinecarboxylic acid hydrochloride

Quantity:
50 mg

Molecular Formula:
C6H5NO2S.HCl

CAS:
320386-54-7

Target:
PCK1

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4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2 H)-phthalazinone

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Chemical Name or Material:
4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2 H)-phthalazinone

Quantity:
50 mg

Molecular Formula:
C24H23FN4O3

CAS:
763113-22-0

Target:
Poly(ADP-ribose) Polymerase Inhibitors